Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
about
The Frizzled family: receptors for multiple signal transduction pathwaysDisulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modulesA novel set of Wnt-Frizzled fusion proteins identifies receptor components that activate beta -catenin-dependent signalingMutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerizationA novel mechanism for Wnt activation of canonical signaling through the LRP6 receptorSecreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agentSecreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancerStructural basis of Wnt recognition by FrizzledWnt modulators in the biotech pipelineWnt signaling: the good and the badThe WntsFrizzled7: A Promising Achilles' Heel for Targeting the Wnt Receptor Complex to Treat CancerMolecular basis of hypohidrotic ectodermal dysplasia: an updateLarge-scale production and protein engineering of G protein-coupled receptors for structural studiesTargeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signalingCrystal Structure of the Frizzled-Like Cysteine-Rich Domain of the Receptor Tyrosine Kinase MuSKStructure of the human smoothened receptor bound to an antitumour agentStructure and function of the Smoothened extracellular domain in vertebrate Hedgehog signalingStructural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signallingThe role of WNT signaling in adult ovarian folliculogenesisSecreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signalingReconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta -catenin signalingPatched acts catalytically to suppress the activity of SmoothenedMUC1 cytoplasmic tail: a potential therapeutic target for ovarian carcinomaAutosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R)Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasisPrediction of structure of human WNT-CRD (FZD) complex for computational drug repurposingDifferential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5aSexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian ductWNT7b mediates macrophage-induced programmed cell death in patterning of the vasculatureRole of the Wnt receptor Frizzled-1 in presynaptic differentiation and functionTranscriptional regulation of the promoter of the rat frizzled related protein gene by CREBA Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotectionMurine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signalingThe evolution of the Wnt pathwayMethylation and loss of Secreted Frizzled-Related Protein 3 enhances melanoma cell migration and invasionAmyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling.Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.
P2860
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P2860
Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@ast
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@en
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@nl
type
label
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@ast
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@en
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@nl
prefLabel
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@ast
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@en
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@nl
P2093
P3181
P356
P1433
P1476
Insights into Wnt binding and ...... Frizzled cysteine-rich domains
@en
P2093
P2888
P3181
P356
10.1038/35083601
P407
P577
2001-07-05T00:00:00Z
P6179
1029025077