Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
about
The AAA+ superfamily of functionally diverse proteinsDocking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entryUnscrambling an egg: protein disaggregation by AAA+ proteinsRecent Advances in Deciphering the Structure and Molecular Mechanism of the AAA+ ATPase N-Ethylmaleimide-Sensitive Factor (NSF)Crystal structure of the heterodimeric complex of the adaptor, ClpS, with the N-domain of the AAA+ chaperone, ClpASolution structure of the dimeric zinc binding domain of the chaperone ClpXBiochemical and Structural Studies of Yeast Vps4 OligomerizationThe Molecular Basis of N-End Rule RecognitionStructural Synergy and Molecular Crosstalk between Bacterial Helicase Loaders and Replication InitiatorsStructural and Motional Contributions of the Bacillus subtilis ClpC N-Domain to Adaptor Protein InteractionsMolecular basis of substrate selection by the N-end rule adaptor protein ClpSA novel ATP-dependent conformation in p97 N–D1 fragment revealed by crystal structures of disease-related mutantsAcyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP.Structure and mechanism of the hexameric MecA-ClpC molecular machineThe ClpS Adaptor Mediates Staged Delivery of N-End Rule Substrates to the AAA+ ClpAP ProteaseStructure of green-type Rubisco activase from tobaccoStructural Dynamics of the MecA-ClpC Complex: A TYPE II AAA+ PROTEIN UNFOLDING MACHINEStructural Insights into the Unusually Strong ATPase Activity of the AAA Domain of the Caenorhabditis elegans Fidgetin-like 1 (FIGL-1) ProteinStructural Basis of Mycobacterial Inhibition by Cyclomarin AElements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motorSpiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocationFundamental Characteristics of AAA+ Protein Family Structure and FunctionAdaptor protein controlled oligomerization activates the AAA+ protein ClpCStructural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47Unfolding and translocation pathway of substrate protein controlled by structure in repetitive allosteric cycles of the ClpY ATPase.Role of a conserved pore residue in the formation of a prehydrolytic high substrate affinity state in the AAA+ chaperone ClpAA single ClpS monomer is sufficient to direct the activity of the ClpA hexamerSubstrate Discrimination by ClpB and Hsp104.Binding of the ClpA unfoldase opens the axial gate of ClpP peptidaseLocal and global mobility in the ClpA AAA+ chaperone detected by cryo-electron microscopy: functional connotations.The ClpP N-terminus coordinates substrate access with protease active site reactivity.Synchrotron protein footprinting supports substrate translocation by ClpA via ATP-induced movements of the D2 loop.The N-end rule pathway and regulation by proteolysisChloroplastic Hsp100 chaperones ClpC2 and ClpD interact in vitro with a transit peptide only when it is located at the N-terminus of a protein.Dynamic and static components power unfolding in topologically closed rings of a AAA+ proteolytic machine.Mechanochemical basis of protein degradation by a double-ring AAA+ machineA camel passes through the eye of a needle: protein unfolding activity of Clp ATPases.Remodelling of VipA/VipB tubules by ClpV-mediated threading is crucial for type VI protein secretionNon-native, N-terminal Hsp70 molecular motor recognition elements in transit peptides support plastid protein translocation.The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes.
P2860
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P2860
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
description
2002 nî lūn-bûn
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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年学术文章
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2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
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name
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@ast
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@en
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@nl
type
label
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@ast
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@en
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@nl
prefLabel
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@ast
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@en
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of ClpA, an Hsp100 chaperone and regulator of ClpAP protease
@en
P2093
Fusheng Guo
Lothar Esser
Michael R Maurizi
P2860
P304
P3181
P356
10.1074/JBC.M207796200
P407
P577
2002-11-29T00:00:00Z