Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor
about
Structural Elements Regulating AAA+ Protein Quality Control Machines.trans-Acting arginine residues in the AAA+ chaperone ClpB allosterically regulate the activity through inter- and intradomain communication.How lamina-associated polypeptide 1 (LAP1) activates Torsin.Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.Structural basis for the disaggregase activity and regulation of Hsp104.Comparative Analysis of the Structure and Function of AAA+ Motors ClpA, ClpB, and Hsp104: Common Threads and Disparate Functions.Mutant Analysis Reveals Allosteric Regulation of ClpB DisaggregaseAvidity for Polypeptide Binding by Nucleotide-Bound Hsp104 Structures.Bi-allelic CLPB mutations cause cataract, renal cysts, nephrocalcinosis and 3-methylglutaconic aciduria, a novel disorder of mitochondrial protein disaggregation.
P2860
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P2860
Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor
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2014 nî lūn-bûn
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2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
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2014年论文
@wuu
name
Elements in nucleotide sensing ...... issection of a molecular motor
@ast
Elements in nucleotide sensing ...... issection of a molecular motor
@en
Elements in nucleotide sensing ...... issection of a molecular motor
@nl
type
label
Elements in nucleotide sensing ...... issection of a molecular motor
@ast
Elements in nucleotide sensing ...... issection of a molecular motor
@en
Elements in nucleotide sensing ...... issection of a molecular motor
@nl
prefLabel
Elements in nucleotide sensing ...... issection of a molecular motor
@ast
Elements in nucleotide sensing ...... issection of a molecular motor
@en
Elements in nucleotide sensing ...... issection of a molecular motor
@nl
P2093
P2860
P3181
P1476
Elements in nucleotide sensing ...... issection of a molecular motor
@en
P2093
Cathleen Zeymer
Jochen Reinstein
Nicolas D Werbeck
Thomas R M Barends
P2860
P304
P3181
P356
10.1107/S1399004713030629
P577
2014-02-01T00:00:00Z