Structure and mechanism of the hexameric MecA-ClpC molecular machine
about
Recent Advances in Deciphering the Structure and Molecular Mechanism of the AAA+ ATPase N-Ethylmaleimide-Sensitive Factor (NSF)Chaperone machines for protein folding, unfolding and disaggregationMolecular Basis for the Unique Role of the AAA+ Chaperone ClpV in Type VI Protein SecretionStructural basis for intersubunit signaling in a protein disaggregating machineStructural Dynamics of the MecA-ClpC Complex: A TYPE II AAA+ PROTEIN UNFOLDING MACHINEStructural Basis of Mycobacterial Inhibition by Cyclomarin AElements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motorHead-to-tail interactions of the coiled-coil domains regulate ClpB activity and cooperation with Hsp70 in protein disaggregationDiscovery of a new motion mechanism of biomotors similar to the earth revolving around the sun without rotation.An atomic structure of the human 26S proteasomeArginine phosphorylation marks proteins for degradation by a Clp proteaseFundamental Characteristics of AAA+ Protein Family Structure and FunctionMechanism of one-way traffic of hexameric phi29 DNA packaging motor with four electropositive relaying layers facilitating antiparallel revolution.The ATPase of the phi29 DNA packaging motor is a member of the hexameric AAA+ superfamily.Revolution rather than rotation of AAA+ hexameric phi29 nanomotor for viral dsDNA packaging without coiling.Structural Elements Regulating AAA+ Protein Quality Control Machines.Common mechanisms of DNA translocation motors in bacteria and viruses using one-way revolution mechanism without rotationD14-SCF(D3)-dependent degradation of D53 regulates strigolactone signalling.Remodeling of a delivery complex allows ClpS-mediated degradation of N-degron substrates.Dynamic and static components power unfolding in topologically closed rings of a AAA+ proteolytic machine.Mechanochemical basis of protein degradation by a double-ring AAA+ machineThe mechanism of Torsin ATPase activation.trans-Acting arginine residues in the AAA+ chaperone ClpB allosterically regulate the activity through inter- and intradomain communication.A pangenomic analysis of the Nannochloropsis organellar genomes reveals novel genetic variations in key metabolic genesHow lamina-associated polypeptide 1 (LAP1) activates Torsin.Proteasomal degradation from internal sites favors partial proteolysis via remote domain stabilization.Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy.Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug designFunctional analysis of conserved cis- and trans-elements in the Hsp104 protein disaggregating machineNew approach to develop ultra-high inhibitory drug using the power function of the stoichiometry of the targeted nanomachine or biocomplex.Biological Nanomotors with a Revolution, Linear, or Rotation Motion MechanismStructure of an endogenous yeast 26S proteasome reveals two major conformational statesStructure of a putative ClpS N-end rule adaptor protein from the malaria pathogen Plasmodium falciparum.Roles of adaptor proteins in regulation of bacterial proteolysisDegradation of SsrA-tagged proteins in streptococci.Differential Regulation of Genes Coding for Organelle and Cytosolic ClpATPases under Biotic and Abiotic Stresses in Wheat.Development of Potent Antiviral Drugs Inspired by Viral Hexameric DNA-Packaging Motors with Revolving Mechanism.Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation.Novel HLA-B27-restricted epitopes from Chlamydia trachomatis generated upon endogenous processing of bacterial proteins suggest a role of molecular mimicry in reactive arthritis.The elusive middle domain of Hsp104 and ClpB: location and function.
P2860
Q26778615-8E7823BD-08EC-4099-840C-95A07F22A3EBQ27026110-FFC7807D-5CD5-448F-B226-89E94F47C2EFQ27670709-7B0475A6-9D4B-4BBB-A6C8-64D08CDDBE1FQ27670764-E1228CBB-8910-4EC3-BF6A-AECF0A62A3C7Q27677434-8ABF5BB6-4886-41E3-98EA-CD537A946D1FQ27679912-C33CF8A4-3248-440D-AAA4-A36ECE744F50Q27681774-9445BA9B-DDA9-4E3A-B0BF-FBB9379EA068Q27683847-246ACCE1-E383-4F4E-B6D3-C26AE44D7257Q27690717-E92A6546-EB4C-4D24-B8D5-F219D7881DD5Q27720380-47902FDD-958F-410F-B99B-BB23DA737EC0Q27728478-567437CB-DDA2-453A-9F03-C565DEC6D4BFQ28066287-2113F240-E98E-411E-AEA9-73F1B300E76CQ30540164-2706EC93-7C81-4FBB-8751-0BABC0DA85A4Q30541135-D79BA2F6-D362-4655-8F94-620B77BED407Q30558609-D6F4CD3B-F7AB-4B18-89CF-6D0AB6A39091Q33634058-EE3534DF-C34F-4BE3-AD18-D3D53173638DQ33736472-F8498636-95D2-48DF-B09C-49938D3847DCQ33896231-1F66C7F9-8B82-4EC5-8A88-1890C3672558Q34218175-36011944-3AC9-4AA5-910F-D82DE67620EBQ34273097-572AE1D0-CA54-4477-8F53-556FF9142738Q34308388-178DEC9F-8D4D-41A6-AF24-018AF80022ECQ34526427-84F2DA27-2473-4676-A765-C57DE707ED80Q34552800-85595DA2-B8AB-4F4F-A24A-4F215E0D514AQ35124814-BBD1EB0E-FC76-4AB8-B6F3-F397F7B9C46FQ35173159-E45D1BD3-E446-41DF-BF0E-D1956DBEBFBCQ35420913-6E39CFBC-686F-4204-A4A8-EFBDD0A9789CQ35910219-C1F53A81-506F-4604-AC97-39EE688826DEQ36061570-DDC1EE60-CB1E-45BD-BCCC-DCAF1C72F453Q36140066-8B6CD25F-2EDF-45A2-A157-F107E0BB1AC9Q36522581-164206EF-DA2C-4300-A66A-7D5BE2AB07A7Q36631415-2ACFA285-2B5B-4278-A537-63A03C9B343BQ36684717-8678F89A-9605-4BE8-A603-14044E634859Q36749676-939D8325-8161-4343-A485-43CFFD519DDFQ36823924-41A8DC01-F014-410D-AE33-9296F7BF81C3Q36871862-4F38B262-A9FC-4925-87A4-0C0CC6732C5EQ37043298-BA789085-AAA9-490A-879F-36BF96FB0994Q37224816-23B40DB4-1248-4B44-8FBB-04550970391EQ37459328-C1EDD72C-845B-4ED0-9D27-07DF41CC017FQ37846210-9B94B1D0-C829-4997-98AE-984A809D554FQ37917880-A31B8B10-5476-4384-9217-40FA5CBDC7FC
P2860
Structure and mechanism of the hexameric MecA-ClpC molecular machine
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@ast
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@en
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@nl
type
label
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@ast
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@en
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@nl
prefLabel
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@ast
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@en
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structure and mechanism of the hexameric MecA-ClpC molecular machine
@en
P2093
P2860
P2888
P3181
P356
10.1038/NATURE09780
P407
P50
P577
2011-03-17T00:00:00Z
P5875
P6179
1000222779