Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase

Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase

Item
http://www.wikidata.org/entity/Q27641862
Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes † ‡Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate ResistanceDesign, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitorsStructural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among speciesSingle agents with designed combination chemotherapy potential: synthesis and evaluation of substituted pyrimido[4,5-b]indoles as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents.Structure and catalytic properties of an engineered heterodimer of enolase composed of one active and one inactive subunit2,4-Diamino-5-(2'-arylpropargyl)pyrimidine derivatives as new nonclassical antifolates for human dihydrofolate reductase inhibition.In pursuit of virtual lead optimization: the role of the receptor structure and ensembles in accurate docking.
P2860

Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase

Item
http://www.wikidata.org/entity/Q27641862
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Analysis of three crystal stru ...... human dihydrofolate reductase
@ast
Analysis of three crystal stru ...... human dihydrofolate reductase
@en
Analysis of three crystal stru ...... human dihydrofolate reductase
@nl
type
label
Analysis of three crystal stru ...... human dihydrofolate reductase
@ast
Analysis of three crystal stru ...... human dihydrofolate reductase
@en
Analysis of three crystal stru ...... human dihydrofolate reductase
@nl
prefLabel
Analysis of three crystal stru ...... human dihydrofolate reductase
@ast
Analysis of three crystal stru ...... human dihydrofolate reductase
@en
Analysis of three crystal stru ...... human dihydrofolate reductase
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P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Analysis of three crystal stru ...... human dihydrofolate reductase
@en
P2093
P304
P31
P356
P433
P478
P577
P698
P921