The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity

The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity

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http://www.wikidata.org/entity/Q27641951
Structure-Activity Relationships and X-ray Structures Describing the Selectivity of Aminopyrazole Inhibitors for c-Jun N-terminal Kinase 3 (JNK3) over p38Synthesis, Biological Evaluation, X-ray Structure, and Pharmacokinetics of Aminopyrimidine c-jun-N-terminal Kinase (JNK) InhibitorsStructure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistanceThe use of biophysical methods increases success in obtaining liganded crystal structuresStructural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.Cross-reactivity virtual profiling of the human kinome by X-react(KIN): a chemical systems biology approachUses for JNK: the many and varied substrates of the c-Jun N-terminal kinases.Anthrapyrazolone analogues intercept inflammatory JNK signals to moderate endotoxin induced septic shock.Enzyme kinetics and interaction studies for human JNK1β1 and substrates activating transcription factor 2 (ATF2) and c-Jun N-terminal kinase (c-Jun).Mitogen activated protein kinase inhibitors: where are we now and where are we going?Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivityA guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets.Automating crystallographic structure solution and refinement of protein-ligand complexes.Considerations of Protein Subpockets in Fragment-Based Drug Design.Arrestin-dependent activation of JNK family kinasesParametrization of halogen bonds in the CHARMM general force field: Improved treatment of ligand-protein interactions.New insights into the structural dynamics of the kinase JNK3.
P2860

The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity

Item
http://www.wikidata.org/entity/Q27641951
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The structure of JNK3 in compl ...... is for potency and selectivity
@ast
The structure of JNK3 in compl ...... is for potency and selectivity
@en
The structure of JNK3 in compl ...... is for potency and selectivity
@nl
type
label
The structure of JNK3 in compl ...... is for potency and selectivity
@ast
The structure of JNK3 in compl ...... is for potency and selectivity
@en
The structure of JNK3 in compl ...... is for potency and selectivity
@nl
prefLabel
The structure of JNK3 in compl ...... is for potency and selectivity
@ast
The structure of JNK3 in compl ...... is for potency and selectivity
@en
The structure of JNK3 in compl ...... is for potency and selectivity
@nl
P1433
P1476
P2093
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P31
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P698
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P1433
P1476
The structure of JNK3 in compl ...... is for potency and selectivity
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P2093
P304
P31
P356
10.1016/S1074-5521(03)00159-5
P433
P478
P50
P577
P698
P921