Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies - Wikidata - wikimedia - TriplyDB

Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies

Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies

http://www.wikidata.org/entity/Q27648851

about

Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor Base ionization and ligand binding: how small ribozymes and riboswitches gain a foothold in a protein world.An Immucillin-Based Transition-State-Analogous Inhibitor of tRNA-Guanine Transglycosylase (TGT).

P2860

Q27653676-674A999F-9987-4B6E-93ED-24A0A4CBC1A6 Q27678289-9C7DC973-02B1-4E06-ACEA-3F1135F4F37D Q35038177-13DB4AF4-F025-439D-82B9-551A21DF43A9 Q53186937-1A6160E0-0F5B-4A1F-8572-87E7AB7BA5AA

P2860

Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies

http://www.wikidata.org/entity/Q27648851

description

2007 nî lūn-bûn

@nan

2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@ast

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@en

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@nl

type

label

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@ast

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@en

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@nl

prefLabel

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@ast

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@en

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@nl

P1433

Q27648851-15DABFE0-54AA-4B7A-AE9B-6A70582620B0

P1476

Q27648851-F635A74C-8029-4EBD-A80C-4AC4DE0A0EAE

P2093

Q27648851-53E9455B-8215-41C8-B19F-9FA0A58A1668

Q27648851-5DF698C1-6EA4-4B68-80F4-C512B33220B0

Q27648851-5EB57CB7-9FDE-422A-A72B-DE803477DAB7

Q27648851-B178813A-702B-4D1C-973C-737C02351707

Q27648851-D1B64DAA-F325-461A-84AC-07326334D21A

P2860

Q27648851-03D42DDB-805D-4901-8727-A3A8A0EA01AA

Q27648851-1456852A-03AD-406B-ADE5-12961C22D827

Q27648851-1B6E100E-8C0C-414F-878F-43FB5C7909E1

Q27648851-1FEE6AAA-059A-4794-BACD-A8421C7D31BE

Q27648851-24C6108F-65D5-42B6-9606-A67A598D556A

Q27648851-36FC46D0-96E5-4052-8255-F082FD6E4B0B

Q27648851-418C9252-E6F2-4506-AEB4-8647189524D9

Q27648851-41B18C70-B9A4-40A0-B5EE-97C546628DCF

Q27648851-4929FBA4-719B-41BC-BFFD-F29A6DFF3950

Q27648851-54B8712B-0122-4E0D-AF9F-3A1AD37A1261

P304

Q27648851-FED30CAA-2B6E-44A3-8BC7-76F6330C4C17

P31

Q27648851-B9F82C45-E4BF-441B-9F39-BFE1049F90A0

P356

Q27648851-26E60608-FA8A-4D8D-AACF-EA6B056AAA63

P407

Q27648851-B8226FDC-EDE6-4E68-BE20-4D13746CBC64

P433

Q27648851-60B2B90D-6A64-460D-B85F-F37A12162543

P478

Q27648851-3188CA96-BD0C-4087-9370-768A0C9F2D4C

P50

Q27648851-A2B476F3-29C3-4C07-9039-EE5EF092CF14

P577

Q27648851-C2550C96-D299-40D1-A6B3-ECB5BFFD29CD

P5875

Q27648851-7355234D-24FC-4E9B-8BD2-9A4AA2B81A02

P698

Q27648851-C25DEE57-78F4-4059-8855-C1EA976E5814

P932

Q27648851-03A4152E-2891-41C2-AB75-B22D4854C266

P356

J.JMB.2007.09.062

P1433

Journal of Molecular Biology

P1476

Glutamate versus Glutamine Exc ...... c and Crystallographic Studies

@en

P2093

Andreas Heine

http://www.w3.org/2001/XMLSchema#string

Bernhard Stengl

http://www.w3.org/2001/XMLSchema#string

George A Garcia

http://www.w3.org/2001/XMLSchema#string

Klaus Reuter

http://www.w3.org/2001/XMLSchema#string

Naomi Tidten

http://www.w3.org/2001/XMLSchema#string

P2860

From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold

Biosynthesis of the modified nucleoside Q in transfer RNA

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Crystal structure of archaeosine tRNA-guanine transglycosylase

Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis

Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate

Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design

Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding

Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange

Coot: model-building tools for molecular graphics

P304

764-76

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.JMB.2007.09.062

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

374

http://www.w3.org/2001/XMLSchema#string

P50

P577

2007-11-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5895458

http://www.w3.org/2001/XMLSchema#string

P698

17949745

http://www.w3.org/2001/XMLSchema#string

P932

2100405

http://www.w3.org/2001/XMLSchema#string