Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers - Wikidata - wikimedia - TriplyDB

Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers

Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers

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Structural probes in quadruplex nucleic acid structure determination by NMR Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G{middle dot}C{middle dot}G{middle dot}C tetrad Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures Fluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation Structure of the human telomere in Na+ solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere Sequence The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination events Cobalt(III)porphyrin to target G-quadruplex DNA.A comparison of four different conformations adopted by human telomeric G-Quadruplex using Computer Simulations.Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD.G-quadruplexes with (4n - 1) guanines in the G-tetrad core: formation of a G-triad·water complex and implication for small-molecule binding Duplex formation at the 5' end affects the quadruplex conformation of the human telomeric repeat overhang in sodium but not in potassium.Stability of telomeric G-quadruplexes.Single-molecule TPM studies on the conversion of human telomeric DNA Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Ball with hair: modular functionalization of highly stable G-quadruplex DNA nano-scaffolds through N2-guanine modification.Exploring the Dynamics of Propeller Loops in Human Telomeric DNA Quadruplexes Using Atomistic Simulations.Structural insights into G-quadruplexes: towards new anticancer drugs.Dynamics and stability of polymorphic human telomeric G-quadruplex under tension.The many twists and turns of DNA: template, telomere, tool, and target.G-quadruplexes are specifically recognized and distinguished by selected designed ankyrin repeat proteins Polycyclic azoniahetarenes: assessing the binding parameters of complexes between unsubstituted ligands and G-quadruplex DNA.DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase.Novel G-quadruplex stabilizing agents: in-silico approach and dynamics.Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions.Single-molecule analysis of thymine dimer-containing G-quadruplexes formed from the human telomere sequence.Loss of loop adenines alters human telomere d[AG3(TTAG3)3] quadruplex folding.Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity.Mechanochemical properties of individual human telomeric RNA (TERRA) G-quadruplexes.Explaining the varied glycosidic conformational, G-tract length and sequence preferences for anti-parallel G-quadruplexes Kinetic partitioning modulates human telomere DNA G-quadruplex structural polymorphism.Mapping the sequences of potential guanine quadruplex motifs.Highly fluorescent guanosine mimics for folding and energy transfer studies G-quadruplexes: from guanine gels to chemotherapeutics A Personal History of Quadruplex-Small Molecule Targeting.Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide-quadruplex complex G-quadruplex structure and stability illuminated by 2-aminopurine phasor plots Separation of Quadruplex Polymorphism in DNA Sequences by Reversed-Phase Chromatography.Molecular engineering of G-quadruplex ligands based on solvent effect of polyethylene glycol.

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Structure of the Human Telomere in K + Solution: A Stable Basket-Type G-Quadruplex with Only Two G-Tetrad Layers

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2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Journal of the American Chemical Society

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Structure of the Human Telomer ...... with Only Two G-Tetrad Layers

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Anh Tuân Phan

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Kah Wai Lim

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Kim Ngoc Luu

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Samir Amrane

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Serge Bouaziz

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Weixin Xu

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Yuguang Mu

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P2860

Quadruplex DNA: sequence, topology and structure

Crystal structure of parallel quadruplexes from human telomeric DNA

Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium.

Covalent ligation studies on the human telomere quadruplex.

Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats

Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal

A diamond-shaped zipper-like DNA architecture containing triads sandwiched between mismatches and tetrads

A two-stranded template-based approach to G.(C-A) triad formation: designing novel structural elements into an existing DNA framework

Structural basis for binding of porphyrin to human telomeres

Structure of a human telomeric DNA sequence stabilized by 8-bromoguanosine substitutions, as determined by NMR in a K+ solution

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4301-9

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scholarly article

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2427299

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10.1021/JA807503G

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12

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Dinshaw J. Patel

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2009-04-01T00:00:00Z

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