Gangliosides as High Affinity Receptors for Tetanus Neurotoxin - Wikidata - wikimedia - TriplyDB

Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

http://www.wikidata.org/entity/Q27656415

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SV2 mediates entry of tetanus neurotoxin into central neurons Lu/BCAM adhesion glycoprotein is a receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1)Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA,The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons Unique Ganglioside Recognition Strategies for Clostridial Neurotoxins Botulinum Neurotoxin Serotype C Associates with Dual Ganglioside Receptors to Facilitate Cell Entry Enhancing the Protective Immune Response against Botulism Glycan microarrays for decoding the glycome.Association analyses of large-scale glycan microarray data reveal novel host-specific substructures in influenza A virus binding glycans Maternal and neonatal tetanus.Tetanus neurotoxin utilizes two sequential membrane interactions for channel formation.Tetanus toxin entry. Nidogens are therapeutic targets for the prevention of tetanus.Preparation and analysis of glycan microarrays Unique ganglioside binding by botulinum neurotoxins C and D-SA A Heterologous Reporter Defines the Role of the Tetanus Toxin Interchain Disulfide in Light-Chain Translocation Tetanus toxin and botulinum toxin a utilize unique mechanisms to enter neurons of the central nervous system Unique biological activity of botulinum D/C mosaic neurotoxin in murine species.General aspects and recent advances on bacterial protein toxins.A dual brain-targeting curcumin-loaded polymersomes ameliorated cognitive dysfunction in intrahippocampal amyloid-β1-42-injected mice.Tetanus Neurotoxin Neutralizing Antibodies Screened from a Human Immune scFv Antibody Phage Display Library Entry of a recombinant, full-length, atoxic tetanus neurotoxin into Neuro-2a cells.Bacterial toxins and the nervous system: neurotoxins and multipotential toxins interacting with neuronal cells.Fragment C of tetanus toxin: new insights into its neuronal signaling pathway.Dissecting the Role of Anti-ganglioside Antibodies in Guillain-Barré Syndrome: an Animal Model Approach.Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons.Biophysical comparison of diphtheria and tetanus toxins with the formaldehyde-detoxified toxoids, the main components of diphtheria and tetanus vaccines.Entry of Botulinum Neurotoxin Subtypes A1 and A2 into Neurons.The structure of the tetanus toxin reveals pH-mediated domain dynamics.Multiple domains of tetanus toxin direct entry into primary neurons.Production and characterization of recombinant light chain and carboxyterminal heavy chain fragments of tetanus toxin.Characterization of neutralizing monoclonal antibodies directed against tetanus toxin fragment C.Exchange of the H(CC) domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin.Protein Structure Facilitates High-Resolution Immunological Mapping.Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.Uptake of Clostridial Neurotoxins into Cells and Dissemination.TeNT HC:LC binds target cell-surface gangliosides Tat-tetanus toxin fragment C: a novel protein delivery vector and its use with photochemical internalization.Engineering Botulinum Toxins to Improve and Expand Targeting and SNARE Cleavage Activity

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

http://www.wikidata.org/entity/Q27656415

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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JBC.M109.027391

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Journal of Biological Chemistry

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Gangliosides as High Affinity Receptors for Tetanus Neurotoxin

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P2093

Chen Chen

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Joseph T Barbieri

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Jung-Ja P Kim

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Michael R Baldwin

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Zhuji Fu

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The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding

Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B

The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin

Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity

The CCP4 suite: programs for protein crystallography

Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophins

Glycan array screening reveals a candidate ligand for Siglec-8

Expression cloning of a human GT3 synthase. GD3 AND GT3 are synthesized by a single enzyme

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

Strategies for macromolecular synchrotron crystallography.

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10.1074/JBC.M109.027391

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