Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
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The role of histone demethylases in cancer therapy8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase InhibitorsLinking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylasesPlant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone DemethylasesA High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase ScreeningSubstituted 2-(2-aminopyrimidin-4-yl)pyridine-4-carboxylates as potent inhibitors of JumonjiC domain-containing histone demethylasesStructural analysis of human KDM5B guides histone demethylase inhibitor developmentEpigenome-based personalized medicine in human cancerModulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectivesThe small molecule JIB-04 disrupts O2 binding in the Fe-dependent histone demethylase KDM4A/JMJD2A.Perspectives on the discovery of small-molecule modulators for epigenetic processes.Targeting histone lysine demethylases - progress, challenges, and the futureSmall-molecular modulators of cancer-associated epigenetic mechanisms.Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitorDocking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.Targeting epigenetic regulations in cancerHistone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.Structural investigations of the nickel-induced inhibition of truncated constructs of the JMJD2 family of histone demethylases using X-ray absorption spectroscopy.Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse CompoundsSmall molecule epigenetic inhibitors targeted to histone lysine methyltransferases and demethylases.Targeting the histone orthography of cancer: drugs for writers, erasers and readers.Epigenetic pathway targets for the treatment of disease: accelerating progress in the development of pharmacological tools: IUPHAR Review 11.Epigenetics: A primer for clinicians.Histone Lysine Demethylase Inhibitors.Epigenetic control and cancer: the potential of histone demethylases as therapeutic targets.Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments.Compounds and methods for inhibiting histone demethylases: a patent evaluation of US20160102096A1.Tetrazolylhydrazides as Selective Fragment-Like Inhibitors of the JumonjiC-Domain-Containing Histone Demethylase KDM4A.Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases
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P2860
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
@ast
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
@en
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
@nl
type
label
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
@ast
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
@en
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
@nl
prefLabel
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
@ast
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
@en
Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds
@nl
P2093
P2860
P50
P356
P1433
P1476
Inhibition of histone demethylases by 4-carboxy-2,2'-bipyridyl compounds
@en
P2093
Anthony Tumber
Kai-Hsuan Chang
Tom D Heightman
P2860
P304
P356
10.1002/CMDC.201100026
P577
2011-03-15T00:00:00Z