Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases

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4-Biphenylalanine- and 3-Phenyltyrosine-Derived Hydroxamic Acids as Inhibitors of the JumonjiC-Domain-Containing Histone Demethylase KDM4A.Tetrazolylhydrazides as Selective Fragment-Like Inhibitors of the JumonjiC-Domain-Containing Histone Demethylase KDM4A.

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Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases

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http://www.wikidata.org/entity/Q57941519

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im Januar 2012 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в січні 2012

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Linking of 2-Oxoglutarate and ...... n of JmjC Histone Demethylases

@en

Linking of 2-Oxoglutarate and ...... n of JmjC Histone Demethylases

@nl

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Item

label

Linking of 2-Oxoglutarate and ...... n of JmjC Histone Demethylases

@en

Linking of 2-Oxoglutarate and ...... n of JmjC Histone Demethylases

@nl

prefLabel

Linking of 2-Oxoglutarate and ...... n of JmjC Histone Demethylases

@en

Linking of 2-Oxoglutarate and ...... n of JmjC Histone Demethylases

@nl

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Linking of 2-Oxoglutarate and ...... n of JmjC Histone Demethylases

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Akane Kawamura

http://www.w3.org/2001/XMLSchema#string

Anthony Tumber

http://www.w3.org/2001/XMLSchema#string

Brian D. Marsden

http://www.w3.org/2001/XMLSchema#string

Christopher J. Schofield

http://www.w3.org/2001/XMLSchema#string

Esther C. Y. Woon

http://www.w3.org/2001/XMLSchema#string

Jerome H. Y. Ma

http://www.w3.org/2001/XMLSchema#string

Ka Hing Che

http://www.w3.org/2001/XMLSchema#string

Lars Hillringhaus

http://www.w3.org/2001/XMLSchema#string

Louise J. Walport

http://www.w3.org/2001/XMLSchema#string

Michael A. McDonough

http://www.w3.org/2001/XMLSchema#string

P2860

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase

Structural basis of the recognition of a methylated histone tail by JMJD2A

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases

Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches

Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds

The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

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1663-1666

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scholarly article

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10.1002/ANGE.201107833

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http://www.w3.org/2001/XMLSchema#string

P478

124

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2012-01-12T00:00:00Z

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Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases

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P2860

P2860

Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases

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P1433

P1476

P2093

P2860

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P356

P433

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P577

P356

P1433

P1476

P2093

P2860

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P31

P356

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