Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds - Wikidata - wikimedia - TriplyDB

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

http://www.wikidata.org/entity/Q37120958

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Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.KDM5 lysine demethylases are involved in maintenance of 3'UTR length.Twenty years of menin: emerging opportunities for restoration of transcription in MEN1.Inhibitors of Protein Methyltransferases and Demethylases.Follicular lymphoma, a B cell malignancy addicted to epigenetic mutations.Molecular structures guide the engineering of chromatin.Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases.The impact of cellular metabolism on chromatin dynamics and epigenetics.JARID1 Histone Demethylases: Emerging Targets in Cancer.Targeting JARID1B's demethylase activity blocks a subset of its functions in oral cancer.Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase.Small molecule KDM4s inhibitors as anti-cancer agents.Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7 KDM5 histone demethylases repress immune response via suppression of STING

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Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

http://www.wikidata.org/entity/Q37120958

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 13 July 2016

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

@en

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.

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type

label

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

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Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.

@nl

prefLabel

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

@en

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.

@nl

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J.CHEMBIOL.2016.06.006

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Cell chemical biology

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Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

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Daniel J Jansen

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Daniel J Urban

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David J Maloney

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Ganesha Rai

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Haian Fu

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John R Shanks

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Joshua S K Bell

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Lizhen Wu

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Margaret A Johns

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Mark J Henderson

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The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

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769-781

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scholarly article

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10.1016/J.CHEMBIOL.2016.06.006

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7

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23

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2016-07-14T00:00:00Z

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27427228

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4958579

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