HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma. - Wikidata - wikimedia - TriplyDB

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

http://www.wikidata.org/entity/Q37387937

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RLIP76 Inhibition: A Promising Developmental Therapy for Neuroblastoma.Protein deubiquitinase USP7 is required for osteogenic differentiation of human adipose-derived stem cells.Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60.Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.Molecular basis of USP7 inhibition by selective small-molecule inhibitors.Ubiquitin carboxyl-terminal hydrolase isozyme L5 inhibits human glioma cell migration and invasion via downregulating SNRPF.Discovery and characterization of highly potent and selective allosteric USP7 inhibitors.Characterization of naturally occurring pentacyclic triterpenes as novel inhibitors of deubiquitinating protease USP7 with anticancer activity in vitro.Targeting HAUSP in both p53 wildtype and p53-mutant tumors.Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.USP49 participates in the DNA damage response by forming a positive feedback loop with p53.USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia

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P2860

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

http://www.wikidata.org/entity/Q37387937

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 12 September 2016

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

@en

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

@nl

type

label

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

@en

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

@nl

prefLabel

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

@en

HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

@nl

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Nature Medicine

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HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.

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Chao Chen

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Chao Dai

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Dawei Li

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Debarshi Banerjee

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Hongbin Sun

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Ning Kon

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Omid Tavana

http://www.w3.org/2001/XMLSchema#string

Wei Gu

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P2860

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

Drugging MYCN through an allosteric transition in Aurora kinase A

The ubiquitin-specific protease USP28 is required for MYC stability

Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma

Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells

Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase

Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein

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1180-1186

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scholarly article

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10.1038/NM.4180

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10

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22

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Andrea Califano

Darrell J Yamashiro

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2016-09-12T00:00:00Z

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1046545483

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27618649

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