The Molecular Mechanism of Hsp100 Chaperone Inhibition by the Prion Curing Agent Guanidinium Chloride
about
Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motorCooperation of Hsp70 and Hsp100 chaperone machines in protein disaggregationSuramin inhibits Hsp104 ATPase and disaggregase activitytrans-Acting arginine residues in the AAA+ chaperone ClpB allosterically regulate the activity through inter- and intradomain communication.Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing.Protein aggregation in Ehrlichia chaffeensis during infection of mammalian cells.Structural basis for the disaggregase activity and regulation of Hsp104.A dominant-negative mutant inhibits multiple prion variants through a common mechanism.Guanidinium export is the primal function of SMR family transporters.
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Q27681774-1CEF8131-4B13-4FC5-9844-F4B4296902A6Q28085237-08C4906D-4941-461C-AD93-20882D31C9F1Q28543672-039DCEB5-1EE4-4CE2-B536-D3C6567451A8Q34552800-C1D0BE90-86EC-4AD1-B273-2B33D9EC8A82Q34729587-B82C01D1-918E-451D-BEF0-319D66EAE941Q38711056-1B728949-24A1-4F67-BADC-9843424651B9Q39143296-CCE0B670-7BC4-4043-BBB5-7509AF546BA1Q46002678-FFBD3135-C5A4-45AF-AA1F-DF8666767A80Q50420766-AB918C65-D92D-4EBA-AF10-9E3413F73A62
P2860
The Molecular Mechanism of Hsp100 Chaperone Inhibition by the Prion Curing Agent Guanidinium Chloride
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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name
The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
@ast
The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
@en
The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
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type
label
The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
@ast
The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
@en
The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
@nl
prefLabel
The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
@ast
The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
@en
The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
@nl
P2093
P2860
P921
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The Molecular Mechanism of Hsp ...... ing Agent Guanidinium Chloride
@en
P2093
Cathleen Zeymer
Jochen Reinstein
Nicolas D Werbeck
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P304
P356
10.1074/JBC.M112.432583
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P577
2013-03-08T00:00:00Z