Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation
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α-Synemin localizes to the M-band of the sarcomere through interaction with the M10 region of titinTherapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorderSignalling scaffolds and local organization of cellular behaviourcAMP-dependent protein kinase (PKA) complexes probed by complementary differential scanning fluorimetry and ion mobility-mass spectrometryThe CaMKII holoenzyme structure in activation-competent conformationsLiberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane SubstratesPseudoscaffolds and anchoring proteins: the difference is in the details.Ca2+/calcineurin-dependent inactivation of neuronal L-type Ca2+ channels requires priming by AKAP-anchored protein kinase A.Protein kinase A catalytic subunit isoform PRKACA; History, function and physiologyA-kinase Anchoring Protein 79/150 Recruits Protein Kinase C to Phosphorylate Roundabout Receptors.PKA-type I selective constrained peptide disruptors of AKAP complexesProtein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to MembranesPINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy.Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma.Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes.The Biological Function of the Prion Protein: A Cell Surface Scaffold of Signaling ModulescAMP signaling in subcellular compartments.FRET biosensors reveal AKAP-mediated shaping of subcellular PKA activity and a novel mode of Ca(2+)/PKA crosstalkAKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution.Discovery of Allostery in PKA Signaling.AKAP-anchored PKA maintains neuronal L-type calcium channel activity and NFAT transcriptional signaling.Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms.Malonate in the nucleotide-binding site traps human AKAP18γ/δ in a novel conformational state.Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivitySignaling at crossroads: the dialogue between PDEs and PKA is spoken in multiple languages.Local protein kinase A action proceeds through intact holoenzymes.Potential for therapeutic targeting of AKAP signaling complexes in nervous system disorders.Mechanisms for restraining cAMP-dependent protein kinase revealed by subunit quantitation and cross-linking approaches.Newly synthesized cAMP is integrated at a membrane protein complex signalosome to ensure receptor response specificity.Control of Homeostatic Synaptic Plasticity by AKAP-Anchored Kinase and Phosphatase Regulation of Ca2+-Permeable AMPA Receptors.A multiscale model for simulating binding kinetics of proteins with flexible linkers.Protein kinase A activation: Something new under the sun?PDE4 and mAKAPβ are nodal organizers of β2-ARs nuclear PKA signaling in cardiac myocytes.Molecular Dissection of Neurobeachin Function at Excitatory Synapses
P2860
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P2860
Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@ast
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@en
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@nl
type
label
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@ast
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@en
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@nl
prefLabel
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@ast
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@en
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@nl
P2860
P50
P3181
P356
P1433
P1476
Intrinsic disorder within an A ...... ocal substrate phosphorylation
@en
P2860
P304
P3181
P356
10.7554/ELIFE.01319
P4011
36f2c237804fa95874a141cc5b3820e298fe5b9b
P407
P577
2013-11-05T00:00:00Z