Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification
about
Nanobodies as Probes for Protein Dynamics in Vitro and in Cells.Interactions between metal-binding domains modulate intracellular targeting of Cu(I)-ATPase ATP7B, as revealed by nanobody binding.Systems approach to metal-based pharmacology.Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor.An omics perspective to the molecular mechanisms of anticancer metallo-drugs in the computational microscope era.Cisplatin inhibits MEK1/2.Copper transporter 2 regulates intracellular copper and sensitivity to cisplatinTargeting copper in cancer therapy: 'Copper That Cancer'.Dynamics of the metal binding domains and regulation of the human copper transporters ATP7B and ATP7A.Copper transporters and chaperones CTR1, CTR2, ATOX1, and CCS as determinants of cisplatin sensitivity.ATP7B expression confers multidrug resistance through drug sequestrationCopper binding modulates the platination of human copper chaperone Atox1 by antitumor trans-platinum complexes.Structural biology of cisplatin complexes with cellular targets: the adduct with human copper chaperone atox1 in aqueous solution.The six metal binding domains in human copper transporter, ATP7B: molecular biophysics and disease-causing mutations.The metal chaperone Atox1 regulates the activity of the human copper transporter ATP7B by modulating domain dynamics.The Structure of Metal Binding Domain 1 of the Copper Transporter ATP7B Reveals Mechanism of a Singular Wilson Disease Mutation.Platination of the copper transporter ATP7A involved in anticancer drug resistance.Platinum transfer from hCTR1 to Atox1 is dependent on the type of platinum complex.Effect of cisplatin on the transport activity of PII-type ATPases.Cisplatin handover between copper transporters: the effect of reducing agents
P2860
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P2860
Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@ast
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@en
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@nl
type
label
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@ast
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@en
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@nl
prefLabel
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@ast
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@en
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@nl
P2093
P2860
P356
P1433
P1476
Copper chaperone Atox1 interac ...... in in cisplatin detoxification
@en
P2093
Corey H Yu
Oleg Y Dmitriev
Sergiy Nokhrin
P2860
P304
P356
10.1042/BJ20121656
P407
P577
2013-08-15T00:00:00Z