Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.
about
Cerebrotendinous xanthomatosis: a comprehensive review of pathogenesis, clinical manifestations, diagnosis, and managementHidden disease susceptibility and sexual dimorphism in the heterozygous knockout of Cyp51 from cholesterol synthesisPolymorphisms of CYP51A1 from cholesterol synthesis: associations with birth weight and maternal lipid levels and impact on CYP51 protein structure.Atherosclerosis susceptibility Loci identified in an extremely atherosclerosis-resistant mouse strain.The Concise Guide to PHARMACOLOGY 2013/14: enzymes.Vertical sleeve gastrectomy reverses diet-induced gene-regulatory changes impacting lipid metabolismGlyphosate, pathways to modern diseases II: Celiac sprue and gluten intoleranceImpact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice.The Associations of Novel Vitamin D3 Metabolic Gene CYP27A1 Polymorphism, Adiponectin/Leptin Ratio, and Metabolic Syndrome in Middle-Aged Taiwanese Males.Identification and analysis of CYP7A1, CYP17A1, CYP20A1, CYP27A1 and CYP51A1 in cynomolgus macaquesThe interaction between metabolism, cancer and cardiovascular disease, connected by 27-hydroxycholesterol.Function of GATA factors in the adult mouse liver.Lessons from hepatocyte-specific Cyp51 knockout mice: impaired cholesterol synthesis leads to oval cell-driven liver injury.Transcriptomic analysis unveils correlations between regulative apoptotic caspases and genes of cholesterol homeostasis in human brain.Hepatic expression of detoxification enzymes is decreased in human obstructive cholestasis due to gallstone biliary obstructionCholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator.Bile acids and their oxo derivatives: Potential inhibitors of carbonic anhydrase I and II, androgen receptor antagonists and CYP3A4 substrates.Dose-response effect of berberine on bile acid profile and gut microbiota in mice.Chronic exposure to rifaximin causes hepatic steatosis in pregnane X receptor-humanized miceRole of Cytochrome P450 Hydroxylase in the Decreased Accumulation of Vitamin E in Muscle from Turkeys Compared to that from Chickens.Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1.Cerebrotendinous xanthomatosis (a rare lipid storage disorder): a case report.Cytochromes p450: roles in diseasesEndogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols.Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1)CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivoCharacterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL-loaded macrophages.Cholesterol, an essential molecule: diverse roles involving cytochrome P450 enzymes.Clinical and molecular genetic features of cerebrotendinous xanthomatosis patients in Chinese families.Molecular dynamics investigations of membrane-bound CYP2C19 polymorphisms reveal distinct mechanisms for peripheral variants by long-range effects on the enzymatic activity.Effects of bile acids on neurological function and disease.Bile acid homeostasis controls CAR signaling pathways in mouse testis through FXRalpha.The roles of bile acids and applications of microencapsulation technology in treating Type 1 diabetes mellitus.Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice.Mitochondrial (dys)function and regulation of macrophage cholesterol efflux.Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice.Epidemiology, diagnosis, and treatment of cerebrotendinous xanthomatosis (CTX).IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis.microRNA-219 Reduces Viral Load and Pathologic Changes in Theiler's Virus-Induced Demyelinating Disease.
P2860
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P2860
Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@ast
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@en
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@nl
type
label
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@ast
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@en
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@nl
prefLabel
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@ast
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@en
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@nl
P2093
P2860
P3181
P1433
P1476
Cytochrome P450s in the synthe ...... ouse models to human diseases.
@en
P2093
Damjana Rozman
Gregor Lorbek
Monika Lewinska
P2860
P304
P3181
P356
10.1111/J.1742-4658.2011.08432.X
P407
P577
2012-05-01T00:00:00Z