Stabilization of Escherichia coli ribonuclease HI by cavity-filling mutations within a hydrophobic core
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Interatomic potentials and solvation parameters from protein engineering data for buried residuesExperimental verification of the 'stability profile of mutant protein' (SPMP) data using mutant human lysozymesFunctional implications from crystal structures of the conserved Bacillus subtilis protein Maf with and without dUTPStabilization of hen egg white lysozyme by a cavity-filling mutationAccommodation of a highly symmetric core within a symmetric protein superfoldStructural and thermodynamic analyses of Escherichia coli RNase HI variant with quintuple thermostabilizing mutationsDestabilization of psychrotrophic RNase HI in a localized fashion as revealed by mutational and X-ray crystallographic analysesStructural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilusActivity, stability, and structure of metagenome-derived LC11-RNase H1, a homolog ofSulfolobus tokodaiiRNase H1Structure and function of an insect -carboxylesterase ( Esterase7) associated with insecticide resistanceCrystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein familyHyperthermophilic enzymes: sources, uses, and molecular mechanisms for thermostabilityDesign of highly stable functional GroEL minichaperones.Recent advances in our understanding of protein conformational stability from a pharmaceutical perspective.Energetics of aliphatic deletions in protein coresCa(2+)-binding reduces conformational flexibility of RC-LH1 core complex from thermophile Thermochromatium tepidum.Inferring stabilizing mutations from protein phylogenies: application to influenza hemagglutinin.Structure of an archaeal virus capsid protein reveals a common ancestry to eukaryotic and bacterial virusesMutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoproteinExceptionally potent and broadly cross-reactive, bispecific multivalent HIV-1 inhibitors based on single human CD4 and antibody domains.Conformational preferences underlying reduced activity of a thermophilic ribonuclease H.An inserted Gly residue fine tunes dynamics between mesophilic and thermophilic ribonucleases HStructural distribution of stability in a thermophilic enzymeHydrophobic core mutations associated with cataract development in mice destabilize human gammaD-crystallin.Protein-protein and peptide-protein docking and refinement using ATTRACT in CAPRI.Crystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy.Rational stabilization of complex proteins: a divide and combine approach.Analysis of a conserved hydrophobic pocket important for the thermostability of Bacillus pumilus chloramphenicol acetyltransferase (CAT-86).Simple models for nonpolar solvation: Parameterization and testing.Computational analysis of the thermal stability in thioredoxins: a molecular dynamics approach.Conformational stabilities of Escherichia coli RNase HI variants with a series of amino acid substitutions at a cavity within the hydrophobic core.
P2860
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P2860
Stabilization of Escherichia coli ribonuclease HI by cavity-filling mutations within a hydrophobic core
description
1993 nî lūn-bûn
@nan
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Stabilization of Escherichia c ...... ions within a hydrophobic core
@ast
Stabilization of Escherichia c ...... ions within a hydrophobic core
@en
Stabilization of Escherichia c ...... ions within a hydrophobic core
@nl
type
label
Stabilization of Escherichia c ...... ions within a hydrophobic core
@ast
Stabilization of Escherichia c ...... ions within a hydrophobic core
@en
Stabilization of Escherichia c ...... ions within a hydrophobic core
@nl
prefLabel
Stabilization of Escherichia c ...... ions within a hydrophobic core
@ast
Stabilization of Escherichia c ...... ions within a hydrophobic core
@en
Stabilization of Escherichia c ...... ions within a hydrophobic core
@nl
P2093
P356
P1433
P1476
Stabilization of Escherichia c ...... ions within a hydrophobic core
@en
P2093
P304
P356
10.1021/BI00075A009
P407
P577
1993-06-22T00:00:00Z