Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family
about
Structural basis of BFL-1 for its interaction with BAX and its anti-apoptotic action in mammalian and yeast cellsTumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19KThe structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activityUnique structural features of a BCL-2 family protein CED-9 and biophysical characterization of CED-9/EGL-1 interactionsStructural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral BCL-2 of Murine γ-Herpesvirus 68Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XLControl of cellular Bcl-xL levels by deamidation-regulated degradationA splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitroRegulation of the cell cycle and apoptosis by the oncogenes of adenovirusStructural effects of protein aging: terminal marking by deamidation in human triosephosphate isomerase.Intrinsically disordered proteins in bcl-2 regulated apoptosis.Bacterial cell death induced by human pro-apoptotic Bax is blocked by an RNase E mutant that functions in an anti-oxidant pathway.DNA damage-induced Bcl-xL deamidation is mediated by NHE-1 antiport regulated intracellular pH.Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.Bcl-2 family proteins as targets for anticancer drug design.Protection against ischemic brain injury by protein therapeutics.Structural studies of apoptosis and ion transport regulatory proteins in membranesBcl-2 is a monomeric protein: prevention of homodimerization by structural constraints.Peptides in apoptosis research.Effect of Temperature Downshift on the Transcriptomic Responses of Chinese Hamster Ovary Cells Using Recombinant Human Tissue Plasminogen Activator Production Culture.Dynamics of the BH3-Only Protein Binding Interface of Bcl-xL.Conversion of cell-survival activity of Akt into apoptotic death of cancer cells by two mutations on the BIM BH3 domain.Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma modelT cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules.N52 monodeamidated Bcl‑xL shows impaired oncogenic properties in vivo and in vitro.The Bcl-2 family: structures, interactions and targets for drug discovery.Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis.Protein asparagine deamidation prediction based on structures with machine learning methodsThe deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane.The microRNA 15a/16-1 cluster down-regulates protein repair isoaspartyl methyltransferase in hepatoma cells: implications for apoptosis regulation.The super anti-apoptotic factor Bcl-xFNK constructed by disturbing intramolecular polar interactions in rat Bcl-xL.Interleukin-3 induces the phosphorylation of a distinct fraction of bcl-2.Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM.Detrimental effects of antiapoptotic treatments in spinal cord injury.Cytochrome c depletion upon expression of Bcl-XS.Biologically distinct conformations of Bcl-x can be resolved using 2D isoelectric focusing.N-terminal deletion augments the cell-death-inducing activity of BAX in adenoviral gene delivery to nonsmall cell lung cancers.Structural conservation of residues in BH1 and BH2 domains of Bcl-2 family proteins.Neuron-specific Bcl-2 homology 3 domain-only splice variant of Bak is anti-apoptotic in neurons, but pro-apoptotic in non-neuronal cells.A trace amount of the human pro-apoptotic factor Bax induces bacterial death accompanied by damage of DNA.
P2860
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P2860
Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@ast
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@en
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@nl
type
label
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@ast
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@en
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@nl
prefLabel
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@ast
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@en
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@nl
P2093
P2860
P921
P356
P1476
Crystal structure of rat Bcl-x ...... on of the Bcl-2 protein family
@en
P2093
P2860
P304
27886-27892
P356
10.1074/JBC.272.44.27886
P407
P577
1997-10-01T00:00:00Z