Structure and function of the dihydropteroate synthase from Staphylococcus aureus - Wikidata - wikimedia - TriplyDB

Structure and function of the dihydropteroate synthase from Staphylococcus aureus

Structure and function of the dihydropteroate synthase from Staphylococcus aureus

http://www.wikidata.org/entity/Q27737332

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Quod erat demonstrandum? The mystery of experimental validation of apparently erroneous computational analyses of protein sequences 2.0 A X-ray structure of the ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase Structural and Kinetic Characterization of 4-Hydroxy-4-methyl-2-oxoglutarate/4-Carboxy-4-hydroxy-2-oxoadipate Aldolase, a Protocatechuate Degradation Enzyme Evolutionarily Convergent with the HpaI and DmpG Pyruvate Aldolases Crystal Structure of the 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase•Dihydropteroate Synthase Bifunctional Enzyme from Francisella tularensis Crystal structures of Burkholderia cenocepacia dihydropteroate synthase in the apo-form and complexed with the product 7,8-dihydropteroate Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase.Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus 3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes Catalysis of methyl group transfers involving tetrahydrofolate and B(12)Cloning and expression of Mycobacterium tuberculosis and Mycobacterium leprae dihydropteroate synthase in Escherichia coli Targeting purine and pyrimidine metabolism in human apicomplexan parasites Mutational analysis of the tetrahydrobiopterin-binding site in inducible nitric-oxide synthase.Functional specificity lies within the properties and evolutionary changes of amino acids Characterization of mutations contributing to sulfathiazole resistance in Escherichia coli.Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria High prevalence of dihydropteroate synthase mutations in Pneumocystis jirovecii isolated from patients with Pneumocystis pneumonia in South Africa.Simultaneous detection of Mycobacterium leprae and its susceptibility to dapsone using DNA heteroduplex analysis.Sulfonamide resistance in clinical isolates of Campylobacter jejuni: mutational changes in the chromosomal dihydropteroate synthase Novel expansions of the gene encoding dihydropteroate synthase in trimethoprim-sulfamethoxazole-resistant Streptococcus pneumoniae.Dihydropteroate synthase of Mycobacterium leprae and dapsone resistance.para-Aminobenzoic acid is a precursor in coenzyme Q6 biosynthesis in Saccharomyces cerevisiae.Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States Sulfonamide resistance in Haemophilus influenzae mediated by acquisition of sul2 or a short insertion in chromosomal folP.Mutation analysis of the Mycobacterium leprae folP1 gene and dapsone resistance.The folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery.Replacing sulfa drugs with novel DHPS inhibitors Genetics of antimicrobial resistance in Staphylococcus aureus.Dihydropteroate synthase mutations in Pneumocystis jiroveci can affect sulfamethoxazole resistance in a Saccharomyces cerevisiae model.Synthesis of bi-substrate state mimics of dihydropteroate synthase as potential inhibitors and molecular probes.Healthcare- and Community-Associated Methicillin-Resistant Staphylococcus aureus (MRSA) and Fatal Pneumonia with Pediatric Deaths in Krasnoyarsk, Siberian Russia: Unique MRSA's Multiple Virulence Factors, Genome, and Stepwise Evolution.Characterization of a novel bifunctional dihydropteroate synthase/dihydropteroate reductase enzyme from Helicobacter pylori Identification of the Final Two Genes Functioning in Methanofuran Biosynthesis in Methanocaldococcus jannaschii.Binding Isotope Effects for para-Aminobenzoic Acid with Dihydropteroate Synthase from Staphylococcus aureus and Plasmodium falciparum Folate metabolism as a source of molecular targets for antimalarials.Role of folate antagonists in the treatment of methicillin-resistant Staphylococcus aureus infection.Dynamically driven protein allostery.

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P2860

Structure and function of the dihydropteroate synthase from Staphylococcus aureus

http://www.wikidata.org/entity/Q27737332

description

1997 nî lūn-bûn

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1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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1997 թվականի ապրիլին հրատարակված գիտական հոդված

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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Structure and function of the dihydropteroate synthase from Staphylococcus aureus

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A D'Arcy

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C Oefner

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