Prp31p promotes the association of the U4/U6 x U5 tri-snRNP with prespliceosomes to form spliceosomes in Saccharomyces cerevisiae.
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Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing.Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteinsSMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome.Tri-snRNP-associated proteins interact with subunits of the TRAMP and nuclear exosome complexes, linking RNA decay and pre-mRNA splicingA Sm-like protein complex that participates in mRNA degradationStructure and function of archaeal box C/D sRNP core proteinsPurification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.The Clf1p splicing factor promotes spliceosome assembly through N-terminal tetratricopeptide repeat contacts.Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activationAlternative splicing and retinal degenerationMutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells.Dominant PRPF31 mutations are hypostatic to a recessive CNOT3 polymorphism in retinitis pigmentosa: a novel phenomenon of "linked trans-acting epistasis".Mutant Prpf31 causes pre-mRNA splicing defects and rod photoreceptor cell degeneration in a zebrafish model for Retinitis pigmentosa.Multiple genetic and biochemical interactions of Brr2, Prp8, Prp31, Prp1 and Prp4 kinase suggest a function in the control of the activation of spliceosomes in Schizosaccharomyces pombe.Transcriptional regulation of PRPF31 gene expression by MSR1 repeat elements causes incomplete penetrance in retinitis pigmentosa.Pre-mRNA splicing and retinitis pigmentosaWhole exome sequencing of a dominant retinitis pigmentosa family identifies a novel deletion in PRPF31Variant haploinsufficiency and phenotypic non-penetrance in PRPF31-associated retinitis pigmentosa.Isolation of an essential Schizosaccharomyces pombe gene, prp31(+), that links splicing and meiosis.Identification of photoreceptor genes affected by PRPF31 mutations associated with autosomal dominant retinitis pigmentosa.Involvement of the spliceosomal U4 small nuclear RNA in heterochromatic gene silencing at fission yeast centromeres.Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation.
P2860
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P2860
Prp31p promotes the association of the U4/U6 x U5 tri-snRNP with prespliceosomes to form spliceosomes in Saccharomyces cerevisiae.
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@ast
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@en
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@nl
type
label
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@ast
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@en
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@nl
altLabel
Prp31p promotes the associatio ...... es in Saccharomyces cerevisiae
@en
prefLabel
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@ast
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@en
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@nl
P2093
P2860
P356
P1476
Prp31p promotes the associatio ...... s in Saccharomyces cerevisiae.
@en
P2093
E M Weidenhammer
J L Woolford
M Ruiz-Noriega
P2860
P304
P356
10.1128/MCB.17.7.3580
P407
P577
1997-07-01T00:00:00Z