Scavenger decapping activity facilitates 5' to 3' mRNA decay
about
7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activityMutations in DCPS and EDC3 in autosomal recessive intellectual disability indicate a crucial role for mRNA decapping in neurodevelopmentDcpS as a therapeutic target for spinal muscular atrophy.DcpS scavenger decapping enzyme can modulate pre-mRNA splicingMechanistic and kinetic analysis of the DcpS scavenger decapping enzymeIdentification of a quality-control mechanism for mRNA 5'-end capping.Activation of 5'-3' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast.Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defectsQuality control of assembly-defective U1 snRNAs by decapping and 5'-to-3' exonucleolytic digestion.Role of the DHH1 gene in the regulation of monocarboxylic acids transporters expression in Saccharomyces cerevisiae.Elimination of cap structures generated by mRNA decay involves the new scavenger mRNA decapping enzyme Aph1/FHIT together with DcpS.DcpS is a transcript-specific modulator of RNA in mammalian cells.Affinity resins containing enzymatically resistant mRNA cap analogs--a new tool for the analysis of cap-binding proteins.The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans.XRN 5'→3' exoribonucleases: structure, mechanisms and functions.RNA degradation in Saccharomyces cerevisaeAnalysis of decapping scavenger cap complex using modified cap analogs reveals molecular determinants for efficient cap binding.T-cell Intracellular Antigen-1 (TIA-1)-induced Translational Silencing Promotes the Decay of Selected mRNAs
P2860
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P2860
Scavenger decapping activity facilitates 5' to 3' mRNA decay
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Scavenger decapping activity facilitates 5' to 3' mRNA decay
@ast
Scavenger decapping activity facilitates 5' to 3' mRNA decay
@en
Scavenger decapping activity facilitates 5' to 3' mRNA decay.
@nl
type
label
Scavenger decapping activity facilitates 5' to 3' mRNA decay
@ast
Scavenger decapping activity facilitates 5' to 3' mRNA decay
@en
Scavenger decapping activity facilitates 5' to 3' mRNA decay.
@nl
prefLabel
Scavenger decapping activity facilitates 5' to 3' mRNA decay
@ast
Scavenger decapping activity facilitates 5' to 3' mRNA decay
@en
Scavenger decapping activity facilitates 5' to 3' mRNA decay.
@nl
P2860
P1476
Scavenger decapping activity facilitates 5' to 3' mRNA decay
@en
P2093
P2860
P304
P356
10.1128/MCB.25.22.9764-9772.2005
P407
P577
2005-11-01T00:00:00Z