Asymmetrical recognition and activity of the I-SceI endonuclease on its site and on intron-exon junctions.
about
BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repairHoming endonucleases: keeping the house in orderReplacement of two non-adjacent amino acids in the S.cerevisiae bi2 intron-encoded RNA maturase is sufficient to gain a homing-endonuclease activityDNA substrate specificity and cleavage kinetics of an archaeal homing-type endonuclease from Pyrobaculum organotrophumThe site-specific DNA endonuclease encoded by a group I intron in the Chlamydomonas pallidostigmatica chloroplast small subunit rRNA gene introduces a single-strand break at low concentrations of Mg2+Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombinationIn vivo selection of engineered homing endonucleases using double-strand break induced homologous recombinationA highly sensitive selection method for directed evolution of homing endonucleases.I-ApeKI [corrected]: a novel intron-encoded LAGLIDADG homing endonuclease from the archaeon, Aeropyrum pernix K1Coevolution of a Homing Endonuclease and Its Host Target SequenceCrystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathwayCrystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineeringOptimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradationExpanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence spaceThe endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivoLimiting the persistence of a chromosome break diminishes its mutagenic potential.Genetic analysis of the Chlamydomonas reinhardtii I-CreI mobile intron homing system in Escherichia coliA novel engineered meganuclease induces homologous recombination in yeast and mammalian cellsThe meganuclease I-SceI containing nuclear localization signal (NLS-I-SceI) efficiently mediated mammalian germline transgenesis via embryo cytoplasmic microinjectionNatural and engineered nicking endonucleases--from cleavage mechanism to engineering of strand-specificityThe mitochondrial LSU rRNA group II intron of Ustilago maydis encodes an active homing endonuclease likely involved in intron mobility.A natural meiotic DNA break site in Schizosaccharomyces pombe is a hotspot of gene conversion, highly associated with crossing over.The homologous chromosome is an effective template for the repair of mitotic DNA double-strand breaks in Drosophila.Evolutionarily conserved and functionally important residues in the I-CeuI homing endonucleaseStatistical modeling and analysis of the LAGLIDADG family of site-specific endonucleases and identification of an intein that encodes a site-specific endonuclease of the HNH familyCoincident resection at both ends of random, γ-induced double-strand breaks requires MRX (MRN), Sae2 (Ctp1), and Mre11-nucleaseEndonuclease-induced, targeted homologous extrachromosomal recombination in Xenopus oocytes.Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing.Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cellsMeganuclease and transposon mediated transgenesis in medaka.Related homing endonucleases I-BmoI and I-TevI use different strategies to cleave homologous recognition sitesThe Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.Precise Editing of the Zebrafish Genome Made Simple and Efficient.Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease.Engineering variants of the I-SceI homing endonuclease with strand-specific and site-specific DNA-nicking activity.Characterization of Mycobacterium leprae RecA intein, a LAGLIDADG homing endonuclease, reveals a unique mode of DNA binding, helical distortion, and cleavage compared with a canonical LAGLIDADG homing endonucleaseImproved cre reporter transgenic Xenopus.Precise genome editing by homologous recombination.Two different but related mechanisms are used in plants for the repair of genomic double-strand breaks by homologous recombination.Purification, biochemical characterization and protein-DNA interactions of the I-CreI endonuclease produced in Escherichia coli.
P2860
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P2860
Asymmetrical recognition and activity of the I-SceI endonuclease on its site and on intron-exon junctions.
description
1993 nî lūn-bûn
@nan
1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
name
Asymmetrical recognition and a ...... and on intron-exon junctions.
@ast
Asymmetrical recognition and a ...... and on intron-exon junctions.
@en
Asymmetrical recognition and a ...... and on intron-exon junctions.
@nl
type
label
Asymmetrical recognition and a ...... and on intron-exon junctions.
@ast
Asymmetrical recognition and a ...... and on intron-exon junctions.
@en
Asymmetrical recognition and a ...... and on intron-exon junctions.
@nl
prefLabel
Asymmetrical recognition and a ...... and on intron-exon junctions.
@ast
Asymmetrical recognition and a ...... and on intron-exon junctions.
@en
Asymmetrical recognition and a ...... and on intron-exon junctions.
@nl
P2093
P2860
P1433
P1476
Asymmetrical recognition and a ...... and on intron-exon junctions.
@en
P2093
P2860
P304
P407
P577
1993-07-01T00:00:00Z