SEACing the GAP that nEGOCiates TORC1 activation: evolutionary conservation of Rag GTPase regulation.
about
Conserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signalingNutrient-sensing mechanisms across evolutionMolecular architecture and function of the SEA complex, a modulator of the TORC1 pathway.Genomic Analysis of ATP Efflux in Saccharomyces cerevisiae.Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling.SZT2 dictates GATOR control of mTORC1 signalling.Tracing the Archaeal Origins of Eukaryotic Membrane-Trafficking System Building Blocks.Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae.TORC1 regulators Iml1/GATOR1 and GATOR2 control meiotic entry and oocyte development in Drosophila.SEA you later alli-GATOR--a dynamic regulator of the TORC1 stress response pathway.Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomesTryptophan-Dependent Control of Colony Formation After DNA Damage via Sea3-Regulated TORC1 Signaling in Saccharomyces cerevisiae.The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission YeastDynamic relocation of the TORC1-Gtr1/2-Ego1/2/3 complex is regulated by Gtr1 and Gtr2.Multiple amino acid sensing inputs to mTORC1.Cystinosin is a Component of the Vacuolar H+-ATPase-Ragulator-Rag Complex Controlling Mammalian Target of Rapamycin Complex 1 Signaling.Unsolved mysteries of Rag GTPase signaling in yeast.The GATOR1 Complex Regulates Metabolic Homeostasis and the Response to Nutrient Stress in Drosophila melanogaster.Rag GTPase in amino acid signaling.Nutrient sensing and TOR signaling in yeast and mammals.The role of genetic testing in epilepsy diagnosis and management.Multiple Targets on the Gln3 Transcription Activator Are Cumulatively Required for Control of Its Cytoplasmic Sequestration.Functional Metabolomics Describes the Yeast Biosynthetic Regulome.The Architecture of the Rag GTPase Signaling Network.Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.Knockout of the epilepsy gene Depdc5 in mice causes severe embryonic dysmorphology with hyperactivity of mTORC1 signalling.SESTRINs regulate mTORC1 via RRAGs: The riddle of GATORPhosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition.Tumor suppressor NPRL2 induces ROS production and DNA damage response.Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases.Amino acid and small GTPase regulation of mTORC1.Genetic dissection of early endosomal recycling highlights a TORC1-independent role for Rag GTPases.Regulation of Sensing, Transportation, and Catabolism of Nitrogen Sources in Saccharomyces cerevisiae.The yeast H+-ATPase Pma1 promotes Rag/Gtr-dependent TORC1 activation in response to H+-coupled nutrient uptake.Seh1 targets GATOR2 and Nup153 to mitotic chromosomes.
P2860
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P2860
SEACing the GAP that nEGOCiates TORC1 activation: evolutionary conservation of Rag GTPase regulation.
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@ast
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@en
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@nl
type
label
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@ast
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@en
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@nl
prefLabel
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@ast
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@en
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@nl
P2860
P921
P3181
P356
P1433
P1476
SEACing the GAP that nEGOCiate ...... tion of Rag GTPase regulation.
@en
P2093
Marie-Pierre Péli-Gulli
Nicolas Panchaud
P2860
P304
P3181
P356
10.4161/CC.26000
P407
P577
2013-09-15T00:00:00Z