RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
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Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repairRAD50 and NBS1 form a stable complex functional in DNA binding and tetheringNbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complexDNA end resection: many nucleases make light workCrystal structure and biochemical analysis of the MutS.ADP.beryllium fluoride complex suggests a conserved mechanism for ATP interactions in mismatch repairThe Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break RepairATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complexXrs2p regulates Mre11p translocation to the nucleus and plays a role in telomere elongation and meiotic recombination.Yeast xrs2 binds DNA and helps target rad50 and mre11 to DNA ends.Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing.Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiaeSupport for a meiotic recombination initiation complex: interactions among Rec102p, Rec104p, and Spo11pRad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes.The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance.Interaction of Mre11 and Rad50: two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae.DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex.NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeresRAD50, an SMC family member with multiple roles in DNA break repair: how does ATP affect function?Mutations in the MRE11, RAD50, XRS2, and MRE2 genes alter chromatin configuration at meiotic DNA double-stranded break sites in premeiotic and meiotic cellsRole of RAD52 epistasis group genes in homologous recombination and double-strand break repairDDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.Prospects for the precise engineering of plant genomes by homologous recombination.Sex and the single cell: meiosis in yeastMre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine.Suppressor analysis of the Saccharomyces cerevisiae gene REC104 reveals a genetic interaction with REC102The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeastThe actin depolymerizing factor (ADF)/cofilin signaling pathway and DNA damage responses in cancerIdentification of Mre11 as a target for heat radiosensitization.Double-stranded DNA breaks and gene functions in recombination and meiosis.Relationship between nuclease-hypersensitive sites and meiotic recombination hot spot activity at the HIS4 locus of Saccharomyces cerevisiae.Requirement of POL3 and POL4 on non-homologous and microhomology-mediated end joining in rad50/xrs2 mutants of Saccharomyces cerevisiae.ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complexCoprinus cinereus rad50 mutants reveal an essential structural role for Rad50 in axial element and synaptonemal complex formation, homolog pairing and meiotic recombinationSharpening the ends for repair: mechanisms and regulation of DNA resection.Meiosis: how could it work?The MRE11 complex: starting from the ends.Fission yeast Dna2 is required for generation of the telomeric single-strand overhangMouse RAD50 has limited epitopic homology to p53 and is expressed in the adult myocardium.Consider the workhorse: Nonhomologous end-joining in budding yeast.DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP.
P2860
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P2860
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
description
1993 nî lūn-bûn
@nan
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@ast
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@en
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@nl
type
label
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@ast
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@en
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@nl
prefLabel
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@ast
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@en
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@nl
P2860
P356
P1476
RAD50 protein of S.cerevisiae exhibits ATP-dependent DNA binding.
@en
P2093
N Kleckner
W E Raymond
P2860
P304
P356
10.1093/NAR/21.16.3851
P407
P577
1993-08-11T00:00:00Z