The human type I interferon receptor. Identification of the interferon beta-specific receptor-associated phosphoprotein
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IFN-beta induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7Different effects of rat interferon alpha, beta and gamma on rat hepatic stellate cell proliferation and activationThe crystal structure of human interferon beta at 2.2-A resolutionStat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signalingCatalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinaseIFN-zeta/ limitin: a member of type I IFN with mild lympho-myelosuppression.Type I Interferons Function as Autocrine and Paracrine Factors to Induce Autotaxin in Response to TLR Activation.STAT3 complements defects in an interferon-resistant cell line: evidence for an essential role for STAT3 in interferon signaling and biological activitiesActivation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß.Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex.Ligand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity.Multifarious determinants of cytokine receptor signaling specificity.Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta.Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation.Impaired antiviral response and alpha/beta interferon induction in mice lacking beta interferon.Response of pancreatic cancer cells treated with interferon-alpha or beta and co-exposed to ionising radiation.Effects of type I interferons on IGF-mediated autocrine/paracrine growth of human neuroendocrine tumor cells.Interferon signaling is dependent on specific tyrosines located within the intracellular domain of IFNAR2c. Expression of IFNAR2c tyrosine mutants in U5A cells.Role of the intracellular domain of the human type I interferon receptor 2 chain (IFNAR2c) in interferon signaling. Expression of IFNAR2c truncation mutants in U5A cells.p95(vav) associates with the type I interferon (IFN) receptor and contributes to the antiproliferative effect of IFN-alpha in megakaryocytic cell lines.Interferonβ-1b Induces the Expression of RGS1 a Negative Regulator of G-Protein Signaling.Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.IFN-β-specific signaling via a unique IFNAR1 interaction.Anti-inflammatory action of type I interferons deduced from mice expressing interferon beta.Growth control mechanisms in multiple myeloma.Longitudinal system-based analysis of transcriptional responses to type I interferons.Induction of beta-R1/I-TAC by interferon-beta requires catalytically active TYK2.Dimerization of the interferon type I receptor IFNaR2-2 is sufficient for induction of interferon effector genes but not for full antiviral activity.USP18 establishes the transcriptional and anti-proliferative interferon α/β differentialDifferences in Activity between α and β Type I Interferons Explored by Mutational Analysis
P2860
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P2860
The human type I interferon receptor. Identification of the interferon beta-specific receptor-associated phosphoprotein
description
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1996
@ast
im Dezember 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/12/27)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/12/27)
@nl
наукова стаття, опублікована в грудні 1996
@uk
name
The human type I interferon re ...... ptor-associated phosphoprotein
@ast
The human type I interferon re ...... ptor-associated phosphoprotein
@en
The human type I interferon re ...... ptor-associated phosphoprotein
@nl
type
label
The human type I interferon re ...... ptor-associated phosphoprotein
@ast
The human type I interferon re ...... ptor-associated phosphoprotein
@en
The human type I interferon re ...... ptor-associated phosphoprotein
@nl
prefLabel
The human type I interferon re ...... ptor-associated phosphoprotein
@ast
The human type I interferon re ...... ptor-associated phosphoprotein
@en
The human type I interferon re ...... ptor-associated phosphoprotein
@nl
P2093
P2860
P356
P1476
The human type I interferon re ...... ptor-associated phosphoprotein
@en
P2093
D. Russell-Harde
H. D. Perez
L. M. Pfeffer
T. C. Wagner
P2860
P304
33165–33168
P356
10.1074/JBC.271.52.33165
P407
P577
1996-12-27T00:00:00Z