about
Controlling DNA-End Resection: An Emerging Task for Ubiquitin and SUMOInteractive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism.Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1.A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection.RPA-Binding Protein ETAA1 Is an ATR Activator Involved in DNA Replication Stress Response.Sharpening the ends for repair: mechanisms and regulation of DNA resection.Mechanism and regulation of DNA end resection in eukaryotesThe democratization of gene editing: Insights from site-specific cleavage and double-strand break repair.Regulation of Single-Strand Annealing and its Role in Genome Maintenance.The control of DNA repair by the cell cycle.Therapeutic targeting and patient selection for cancers with homologous recombination defects.Cell cycle-dependent control of homologous recombination.DNA2-An Important Player in DNA Damage Response or Just Another DNA Maintenance Protein?BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance.Bi-allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer.How cells ensure correct repair of DNA double-strand breaks.ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair.Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.A family of unconventional deubiquitinases with modular chain specificity determinants.Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks.Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin.The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.Single-Strand Break End Resection in Genome Integrity: Mechanism and Regulation by APE2Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and CancerBRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor ResistanceSHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choiceThe shieldin complex mediates 53BP1-dependent DNA repairUbiquitylation at the Fork: Making and Breaking Chains to Complete DNA Replication
P2860
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P2860
description
2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2016
@ast
im Februar 2016 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2016/02/04)
@sk
vědecký článek publikovaný v roce 2016
@cs
wetenschappelijk artikel (gepubliceerd op 2016/02/04)
@nl
наукова стаття, опублікована в лютому 2016
@uk
مقالة علمية (نشرت في 4-2-2016)
@ar
name
HELB Is a Feedback Inhibitor of DNA End Resection
@ast
HELB Is a Feedback Inhibitor of DNA End Resection
@en
HELB Is a Feedback Inhibitor of DNA End Resection
@nl
type
label
HELB Is a Feedback Inhibitor of DNA End Resection
@ast
HELB Is a Feedback Inhibitor of DNA End Resection
@en
HELB Is a Feedback Inhibitor of DNA End Resection
@nl
prefLabel
HELB Is a Feedback Inhibitor of DNA End Resection
@ast
HELB Is a Feedback Inhibitor of DNA End Resection
@en
HELB Is a Feedback Inhibitor of DNA End Resection
@nl
P2093
P50
P3181
P1433
P1476
HELB Is a Feedback Inhibitor of DNA End Resection
@en
P2093
Abdallah Al-Hakim
Alexandre Orthwein
Cristina Escribano-Díaz
David Gallo
Grant W. Brown
Hemanta Adhikary
Jana Krietsch
Jean-Yves Masson
Jordan T. F. Young
Jos Jonkers
P304
P3181
P356
10.1016/J.MOLCEL.2015.12.013
P577
2016-02-04T00:00:00Z