Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome
about
Down syndrome: searching for the genetic culpritsRegulation of postsynaptic AMPA responses by synaptojanin 1Dissecting Alzheimer disease in Down syndrome using mouse modelsPhosphoinositides: tiny lipids with giant impact on cell regulationTrisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomesProteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapseCharacterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTBPhosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brainSynaptojanin-1 plays a key role in astrogliogenesis: possible relevance for Down's syndromeSynaptojanin cooperates in vivo with endophilin through an unexpected mechanism.A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes.Screening assay for small-molecule inhibitors of synaptojanin 1, a synaptic phosphoinositide phosphatase.Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain.The Sac domain-containing phosphoinositide phosphatases: structure, function, and diseaseIdentification of inhibitors of inositol 5-phosphatases through multiple screening strategies.Phosphoinositide phosphatases in cell biology and disease.The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamicsDescribing the hexapeptide identity platform between the influenza A H5N1 and Homo sapiens proteomes.Abnormal microRNA expression in Ts65Dn hippocampus and whole blood: contributions to Down syndrome phenotypes.Activity-dependent facilitation of Synaptojanin and synaptic vesicle recycling by the Minibrain kinaseGene expression analysis following olfactory learning in Apis mellifera.Down syndrome--recent progress and future prospects.The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.Synaptophysin and synaptojanin-1 in Down syndrome are differentially affected by Alzheimer's diseaseDetection and manipulation of phosphoinositides.Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome.Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal CortexCellular and molecular interactions of phosphoinositides and peripheral proteinsPhosphoinositide control of membrane protein function: a frontier led by studies on ion channels.The use of mouse models for understanding the biology of down syndrome and agingLinking lipids to Alzheimer's disease: cholesterol and beyond.Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer's disease pathogenesis.Molecular and cellular alterations in Down syndrome: toward the identification of targets for therapeuticsMutations in phosphoinositide metabolizing enzymes and human disease.Role of phosphoinositides at the neuronal synapse.Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1)Fig4 deficiency: a newly emerged lysosomal storage disorder?The Voltage Activation of Cortical KCNQ Channels Depends on Global PIP2 Levels.Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21.Down syndrome and Alzheimer's disease: Common pathways, common goals.
P2860
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P2860
Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome
description
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2008
@ast
im Juli 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/07/08)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/07/08)
@nl
наукова стаття, опублікована в липні 2008
@uk
name
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@ast
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@en
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@nl
type
label
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@ast
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@en
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@nl
prefLabel
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@ast
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@en
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@nl
P2093
P2860
P921
P356
P1476
Synaptojanin 1-linked phosphoi ...... ouse models of Down's syndrome
@en
P2093
Cecilia Schmidt
Christelle Borel
Elizabeth A. Pollina
Ellen C. Akeson
Gilbert Di Paolo
Hong Zhang
Katheleen Gardiner
Laurent Cimasoni
Markus R. Wenk
Muriel T. Davisson
P2860
P304
P356
10.1073/PNAS.0803756105
P407
P577
2008-07-08T00:00:00Z