about
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injuryNature's bounty - drug discovery from the seaSemi-automated liquid chromatography-mass spectrometric imaging platform for enhanced detection and improved data analysis of complex peptides.MRMer, an interactive open source and cross-platform system for data extraction and visualization of multiple reaction monitoring experimentsHigh-throughput chiral liquid chromatography/tandem mass spectrometry.High-throughput analysis of everolimus (RAD001) and cyclosporin A (CsA) in whole blood by liquid chromatography/mass spectrometry using a semi-automated 96-well solid-phase extraction system.Use of atmospheric pressure ionization mass spectrometry in enantioselective liquid chromatography.Cassette-accelerated rapid rat screen: a systematic procedure for the dosing and liquid chromatography/atmospheric pressure ionization tandem mass spectrometric analysis of new chemical entities as part of new drug discovery.Analysis of pyridoquinoline derivatives by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry.Quantitative determination of polar and ionic compounds in petroleum fractions by atmospheric pressure chemical ionization and electrospray ionization mass spectrometry.Correlation between y-type ions observed in ion trap and triple quadrupole mass spectrometersMaRiMba: a software application for spectral library-based MRM transition list assembly.A statistical procedure to selectively detect metabolite signals in LC-MS data based on using variable isotope ratios.Rapid optimization of MRM-MS instrument parameters by subtle alteration of precursor and product m/z targets.Direct standard-free quantitation of Tamiflu and other pharmaceutical tablets using clustering agents with electrospray ionization mass spectrometryAn integrated method for degradation products detection and characterization using hybrid ion trap/time-of-flight mass spectrometry and data processing techniques: Application to study of the degradation products of danofloxacin under stressed condimvp - an open-source preprocessor for cleaning duplicate records and missing values in mass spectrometry dataSelected reaction monitoring (SRM) mass spectrometry without isotope labeling can be used for rapid protein quantification.Internal standard strategies for relative and absolute quantitation of peptides in biological matrices by liquid chromatography tandem mass spectrometry.Assigning product ions from complex MS/MS spectra: the importance of mass uncertainty and resolving power.Quantitative mapping of reversible mitochondrial Complex I cysteine oxidation in a Parkinson disease mouse model.Simultaneous quantitation of amino acid mixtures using clustering agents.Determination of a novel phosphodiesterase4 inhibitor, 3-[1-(3cyclopropylmethoxy-4-difluoromethoxybenzyl)-1H-pyrazol-3-yl]-benzoic acid (PDE-423) in rat plasma using liquid chromatography-tandem mass spectrometry.Assessment of tandem mass spectrometry and high-resolution mass spectrometry for the analysis of bupivacaine in plasma.Extraction and chromatography-mass spectrometric analysis of the active principles from selected Chinese herbs and other medicinal plants.Pharmacokinetic and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution MALDI-FTICR-mass spectrometry imaging.Prediction of drug metabolism and interactions on the basis of in vitro investigations.On silico peptide microarrays for high-resolution mapping of antibody epitopes and diverse protein-protein interactions.In vitro screening of drug metabolism during drug development: can we trust the predictions?Characterization of impurities in the bulk drug lisinopril by liquid chromatography/ion trap spectrometryQuantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution.Liquid chromatography-matrix-assisted laser desorption/ionization mass spectrometric imaging with sprayed matrix for improved sensitivity, reproducibility and quantitationIntracellular adaptation of Brucella abortus.A Metabolomic Strategy to Screen the Prototype Components and Metabolites of Shuang-Huang-Lian Injection in Human Serum by Ultra Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry.Recent development in high-throughput bioanalytical support for in vitro ADMET profiling.From known knowns to known unknowns: predicting in vivo drug metabolites.From definition to implementation: a cross-industry perspective of past, current and future MIST strategies.Mass spectrometry for small molecule pharmaceutical product development: a review.Enhancement of the capabilities of liquid chromatography-mass spectrometry with derivatization: general principles and applications.High-field asymmetric waveform ion mobility spectrometry with solvent vapor addition: a potential greener bioanalytical technique.
P2860
Q24657261-A668A9BB-E848-4501-86EE-05ECA56AEE42Q28828257-03C1139E-8678-4A9A-B40F-FDCF0F1BF671Q30620240-27F387D0-A958-46D4-995C-426A4C87813DQ31163848-F9F5A1F6-CD1F-4506-8D06-FA874A1AE293Q33421924-D3D59272-7837-49F9-BCF6-03E98FFFE4EEQ33422532-7AD728A6-8B47-450D-8B71-046C2E8170BFQ33422783-8796F4FB-4C5B-4463-8876-0BBEC48B3EABQ33422934-779EFC39-A154-43DF-91EB-695348152A62Q33423271-9D16C894-30F3-4A2D-BB20-2C4619A9FD42Q33425446-F3077B61-8FDF-48A0-81E7-9A393DF11AF3Q33482345-D2BFB95D-764F-41C3-9178-36E4C2A0FDE1Q33482354-6153A101-45D7-49D0-A885-1E54572B87F3Q33515198-5FF3057B-C464-44F5-87DE-6503BCF5FF9CQ33611832-5FF7D725-04A8-483C-8EA7-50DB3BD81EBCQ33651043-65956B9F-CE25-436D-87F5-D98F51279E5CQ33789975-C2D35FF1-3DE0-4052-910D-E2517E9CB781Q33862968-0F3B435D-01DF-4675-8AAF-42EACE2313A5Q34002689-7FF882B2-9202-4A9A-835E-E512377C6F96Q34310103-52B1634E-D269-4161-BB11-7E9C26B1239AQ34391474-A72108DA-C86C-451A-B5CF-F493FB5E684EQ34606427-5B1D14EA-9AA9-41C7-9D37-60F981B050A5Q34709583-A1EC6450-58F2-4900-868F-12419A4B2831Q35213649-C5E85EF0-CBD7-4F44-B6D4-3785DB474D01Q35627328-E85BBB3E-7484-4238-87FA-CB59F71EF588Q35679002-21538993-E81D-4E62-BFBE-72E08F860B94Q35863164-928F9953-6BCF-496A-AB9C-806BDC674438Q36055562-6770313C-E742-42E7-BCAC-63A77F770A22Q36377207-13959794-637C-4A54-9919-5C6F0A652E5CQ36572626-BDF58C9B-A662-4E65-9E59-C89CFEB00C03Q36632523-6643C017-1748-40E7-B2EE-B26BB830F290Q36731097-B8058A3A-A0E9-4A40-A31E-59BE20FE8E18Q37340446-17996CB0-7AFE-4C44-BA70-1E5877F49E42Q37407711-DA38A9B8-98C0-4625-A610-0B4DA97C1387Q37639700-A47268E5-0ED7-4F9F-83AE-46146850CFA3Q37693962-6AE0706E-76FB-4DFD-B5CB-A93E61B72D71Q37810200-CC92B124-F313-4918-B359-BAC7F46C251AQ37859007-DDFD70F7-A824-4876-8C32-07879172D0FCQ37866229-41B2927D-A444-43CF-B60E-D5A876A8E6B6Q37873880-3F012C37-1A6F-4526-A2D1-5A1E0D36C01EQ38020526-6DBE8723-0DB4-4BFF-AED7-5D83FA35AE2C
P2860
description
1999 nî lūn-bûn
@nan
1999 թուականին հրատարակուած գիտական յօդուած
@hyw
1999 թվականին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
LC/MS applications in drug development
@ast
LC/MS applications in drug development
@en
LC/MS applications in drug development
@nl
type
label
LC/MS applications in drug development
@ast
LC/MS applications in drug development
@en
LC/MS applications in drug development
@nl
prefLabel
LC/MS applications in drug development
@ast
LC/MS applications in drug development
@en
LC/MS applications in drug development
@nl
P2860
P1476
LC/MS applications in drug development
@en
P2093
P2860
P304
P356
10.1002/(SICI)1098-2787(1999)18:3/4<187::AID-MAS2>3.0.CO;2-K
P407
P577
1999-01-01T00:00:00Z