From definition to implementation: a cross-industry perspective of past, current and future MIST strategies. - Wikidata - wikimedia - TriplyDB

From definition to implementation: a cross-industry perspective of past, current and future MIST strategies.

From definition to implementation: a cross-industry perspective of past, current and future MIST strategies.

http://www.wikidata.org/entity/Q37859007

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Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data.Simultaneous identification and quantification of new psychoactive substances in blood by GC-APCI-QTOFMS coupled to nitrogen chemiluminescence detection without authentic reference standards.Radiolabelled mass-balance excretion and metabolism studies in laboratory animals: are they still necessary?Preclinical in vivo ADME studies in drug development: a critical review.The early estimation of circulating drug metabolites in humans.The debate on animal ADME studies in drug development: an update.Applications of mass spectrometry in drug metabolism: 50 years of progress.Human absorption, distribution, metabolism and excretion properties of drug molecules: a plethora of approaches Metabolism-guided drug design

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From definition to implementation: a cross-industry perspective of past, current and future MIST strategies.

http://www.wikidata.org/entity/Q37859007

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 29 March 2011

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

From definition to implementat ...... nt and future MIST strategies.

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From definition to implementat ...... nt and future MIST strategies.

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From definition to implementat ...... nt and future MIST strategies.

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From definition to implementat ...... nt and future MIST strategies.

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From definition to implementat ...... nt and future MIST strategies.

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From definition to implementat ...... nt and future MIST strategies.

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From definition to implementat ...... nt and future MIST strategies.

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Angus N R Nedderman

http://www.w3.org/2001/XMLSchema#string

David Higton

http://www.w3.org/2001/XMLSchema#string

Gordon J Dear

http://www.w3.org/2001/XMLSchema#string

R Scott Obach

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Stephanie North

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P2860

LC/MS applications in drug development

Thermospray liquid chromatography/mass spectrometry determination of drugs and their metabolites in biological fluids

Accelerated throughput metabolic route screening in early drug discovery using high-resolution liquid chromatography/quadrupole time-of-flight mass spectrometry and automated data analysis.

An interface for direct analysis of (14)c in nonvolatile samples by accelerator mass spectrometry.

The use of accelerator mass spectrometry to obtain early human ADME/PK data.

General implementation of the ERETIC method for pulsed field gradient probe heads.

What is the objective of the mass balance study? A retrospective analysis of data in animal and human excretion studies employing radiolabeled drugs.

Quantification and rapid metabolite identification in drug discovery using API time-of-flight LC/MS.

A retention-time-shift-tolerant background subtraction and noise reduction algorithm (BgS-NoRA) for extraction of drug metabolites in liquid chromatography/mass spectrometry data from biological matrices.

An accurate-mass-based spectral-averaging isotope-pattern-filtering algorithm for extraction of drug metabolites possessing a distinct isotope pattern from LC-MS data.

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605-622

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10.3109/00498254.2011.562330

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