Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
about
T6BP, a TRAF6-interacting protein involved in IL-1 signalingEssential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunityCD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cellsIRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinaseMEK5, a new target of the atypical protein kinase C isoforms in mitogenic signalingInterleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathwayThe atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathwayLys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activationInterleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinaseChemoresistance and Cancer-Related Inflammation: Two Hallmarks of Cancer Connected by an Atypical Link, PKCζDeconstructing innate immune signaling in myelodysplastic syndromesA mutation in Irak2c identifies IRAK-2 as a central component of the TLR regulatory network of wild-derived miceIRAK-4 inhibitors for inflammationEssential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signalingDual Inhibition of Rip2 and IRAK1/4 Regulates IL-1β and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear CellsInterleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNAProtein kinase Cepsilon is required for macrophage activation and defense against bacterial infectionInterleukin-1 receptor-associated kinase-2 genetic variant rs708035 increases NF-κB activity through promoting TRAF6 ubiquitinationDynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFalpha-induced inflammatory responsesRegulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning.The atypical protein kinase Cs. Functional specificity mediated by specific protein adaptersMolecular evolution and structural features of IRAK family members.Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy.Human interleukin-1 receptor-associated kinase-2 is essential for Toll-like receptor-mediated transcriptional and post-transcriptional regulation of tumor necrosis factor alphaRacial disparities and sex-based outcomes differences after severe injury.Increased expression of the interleukin-1 receptor-associated kinase (IRAK)-1 is associated with adipose tissue inflammatory state in obesityKaposi's sarcoma-associated herpesvirus microRNAs target IRAK1 and MYD88, two components of the toll-like receptor/interleukin-1R signaling cascade, to reduce inflammatory-cytokine expression.Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections.Toll-like Receptors in the Vascular System: Sensing the Dangers Within.mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells.MicroRNAs and toll-like receptor/interleukin-1 receptor signaling.MicroRNA-146a-mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injuryMechanistic role of microRNA-146a in endotoxin-induced differential cross-regulation of TLR signalingThe interleukin-1 receptor associated kinase 1 contributes to the regulation of NFATThe involvement of the interleukin-1 receptor-associated kinases (IRAKs) in cellular signaling networks controlling inflammationVariant IRAK-1 haplotype is associated with increased nuclear factor-kappaB activation and worse outcomes in sepsisIdentification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.Interleukin-18-related genes are induced during the contraction phase but do not play major roles in regulating the dynamics or function of the T-cell response to Listeria monocytogenes infectionListeria monocytogenes and the Inflammasome: From Cytosolic Bacteriolysis to Tumor ImmunotherapyIRAK1-dependent signaling mediates mortality in polymicrobial sepsis.
P2860
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P2860
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@ast
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@en
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@nl
type
label
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@ast
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@en
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@nl
prefLabel
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@ast
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@en
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@nl
P2093
P1476
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
@en
P2093
J A Thomas
S A Wasserman
T Dubnicoff
P304
P407
P577
1999-07-15T00:00:00Z