DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization
about
Identification and subcellular localization of the RP1 protein in human and mouse photoreceptorsA novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilizationDominant Expression of DCLK1 in Human Pancreatic Cancer Stem Cells Accelerates Tumor Invasion and MetastasisMolecular Basis for Specific Regulation of Neuronal Kinesin-3 Motors by Doublecortin Family ProteinsCre fate mapping reveals lineage specific defects in neuronal migration with loss of Pitx2 function in the developing mouse hypothalamus and subthalamic nucleusA novel role for doublecortin and doublecortin-like kinase in regulating growth cone microtubules.Doublecortin associates with microtubules preferentially in regions of the axon displaying actin-rich protrusive structuresMultisite phosphorylation of doublecortin by cyclin-dependent kinase 5.The evolving doublecortin (DCX) superfamily.Effect of skilled reaching training and enriched environment on generation of oligodendrocytes in the adult sensorimotor cortex and corpus callosum.Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brainDCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorderWhole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory responseEukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoni.Transcriptomic effects of di-(2-ethylhexyl)-phthalate in Syrian hamster embryo cells: an important role of early cytoskeleton disturbances in carcinogenesis?Suppression of dendritic cell-mediated responses by genes in calcium and cysteine protease pathways during Mycobacterium tuberculosis infection.Long-lived intestinal tuft cells serve as colon cancer-initiating cells.Doublecortin and CaM kinase-like-1 and leucine-rich-repeat-containing G-protein-coupled receptor mark quiescent and cycling intestinal stem cells, respectively.The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.New insights into pancreatic cancer stem cells.Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenografts.Honokiol in combination with radiation targets notch signaling to inhibit colon cancer stem cells.Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical ImplicationsInflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseasesDoublecortin-like kinase 1 exhibits cancer stem cell-like characteristics in a human colon cancer cell lineSmall intestinal stem cell markers.Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice.Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities.Selective blockade of DCAMKL-1 results in tumor growth arrest by a Let-7a MicroRNA-dependent mechanism.Guiding neuronal cell migrations.Intestinal stem cells and the colorectal cancer microenvironment.Prediction of gene network models in limb muscle precursors.A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing colon cancer risk after screening colonoscopy.(Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell-Cycle Progression.Functional implication of Dclk1 and Dclk1-expressing cells in cancer.APSA Awardee Submission: Tumor/cancer stem cell marker doublecortin-like kinase 1 in liver diseases.Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.Characterizing the molecular features of ERG-positive tumors in primary and castration resistant prostate cancer.Epigenetic regulation of human DCLK-1 gene during colon-carcinogenesis: clinical and mechanistic implications
P2860
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P2860
DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization
description
2000 nî lūn-bûn
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2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@ast
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@en
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@nl
type
label
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@ast
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@en
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@nl
prefLabel
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@ast
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@en
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@nl
P2093
P1476
DCAMKL1 encodes a protein kina ...... tes microtubule polymerization
@en
P2093
P304
P356
10.1523/JNEUROSCI.20-24-09152.2000
P407
P577
2000-12-15T00:00:00Z