Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
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Wnt Signaling in Cancer Stem Cell BiologyDrug Delivery Using Nanoparticles for Cancer Stem-Like Cell TargetingMouse models of intestinal cancerReserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tractMeasuring stem cell dynamics in the human colon--where there's a wiggle, there's a wayMicroenvironmental control of stem cell fate in intestinal homeostasis and diseaseDominant Expression of DCLK1 in Human Pancreatic Cancer Stem Cells Accelerates Tumor Invasion and MetastasisCurrent understanding concerning intestinal stem cellsEpigenetic regulation of the intestinal epitheliumGastrointestinal stem cell up-to-dateSustained proliferation in cancer: Mechanisms and novel therapeutic targetsThe intestinal tuft cell nanostructure in 3D.Tuft Cells: New Players in Colitis.The Origins of Gastric Cancer From Gastric Stem Cells: LessonsĀ From Mouse Models.Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity.Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity.The secret origins and surprising fates of pancreas tumorsInducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestineTuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transitionThree-Dimensional Gastrointestinal Organoid Culture in Combination with Nerves or Fibroblasts: A Method to Characterize the Gastrointestinal Stem Cell Niche.Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasisVitamin D is a determinant of mouse intestinal Lgr5 stem cell functionsAcute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway.Commensal bacteria drive endogenous transformation and tumour stem cell marker expression through a bystander effect.Denervation suppresses gastric tumorigenesis.DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinomaAblation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis.Colorectal cancer: role of commensal bacteria and bystander effects.High expression of the putative cancer stem cell marker, DCLK1, in rectal neuroendocrine tumors.Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical ImplicationsDoublecortin-like kinase 1-positive enterocyte - a new cell type in human intestine.Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseasesTargeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer.Dormant Intestinal Stem Cells Are Regulated by PTEN and Nutritional StatusDclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewalSelective and reversible suppression of intestinal stem cell differentiation by pharmacological inhibition of BET bromodomainsBcl-2 is a critical mediator of intestinal transformation
P2860
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P2860
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
description
2014 nĆ® lÅ«n-bĆ»n
@nan
2014 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕ”ÖÕæÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
Õ¤ÕøÖÕ”Õ®
@hyw
2014 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ“Õ”ÖÕæÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2014幓ć®č«ę
@ja
2014幓č«ę
@yue
2014幓č«ę
@zh-hant
2014幓č«ę
@zh-hk
2014幓č«ę
@zh-mo
2014幓č«ę
@zh-tw
2014幓č®ŗę
@wuu
name
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@ast
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@en
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@nl
type
label
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@ast
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@en
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@nl
prefLabel
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@ast
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@en
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@nl
P2093
P2860
P50
P356
P1476
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
@en
P2093
Andreas H Nuber
Anna Brandtner
Ashlesha Muley
C Benedikt Westphalen
Courtney W Houchen
James G Fox
Michael D Gershon
Michael Quante
Randal May
Wanda Setlik
P2860
P304
P356
10.1172/JCI73434
P407
P577
2014-03-01T00:00:00Z