Alterations of SAG mRNA in human cancer cell lines: requirement for the RING finger domain for apoptosis protection
about
Yeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination: chip profiling implicates its role in cell cycle regulationPromotion of S-phase entry and cell growth under serum starvation by SAG/ROC2/Rbx2/Hrt2, an E3 ubiquitin ligase component: association with inhibition of p27 accumulationMolecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p.Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis.Inactivation of SAG E3 ubiquitin ligase blocks embryonic stem cell differentiation and sensitizes leukemia cells to retinoid acid.Small RING Finger Proteins RBX1 and RBX2 of SCF E3 Ubiquitin Ligases: The Role in Cancer and as Cancer TargetsE3 ubiquitin ligases as cancer targets and biomarkers.SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protectionSAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradationSCF E3 ubiquitin ligases as anticancer targets.Radiosensitization of Cancer Cells by Inactivation of Cullin-RING E3 Ubiquitin Ligases.Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase.Disruption of Sag/Rbx2/Roc2 induces radiosensitization by increasing ROS levels and blocking NF-kappaB activation in mouse embryonic stem cells.Knockdown of sensitive to apoptosis gene by small interfering RNA enhances the sensitivity of PC3 cells toward actinomycin D and etoposide.Validation of SAG/RBX2/ROC2 E3 ubiquitin ligase as an anticancer and radiosensitizing targetAttenuation of ischemia-induced mouse brain injury by SAG, a redox-inducible antioxidant protein.Quantification of Etoposide Hypersensitivity: A Sensitive, Functional Method for Assessing Pluripotent Stem Cell Quality.
P2860
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P2860
Alterations of SAG mRNA in human cancer cell lines: requirement for the RING finger domain for apoptosis protection
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@ast
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@en
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@nl
type
label
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@ast
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@en
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@nl
prefLabel
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@ast
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@en
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@nl
P356
P1433
P1476
Alterations of SAG mRNA in hum ...... omain for apoptosis protection
@en
P2093
P304
P356
10.1093/CARCIN/20.10.1899
P407
P577
1999-10-01T00:00:00Z