Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption - Wikidata - wikimedia - TriplyDB

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

http://www.wikidata.org/entity/Q28180293

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8-Oxoguanine DNA glycosylase (OGG1) deficiency increases susceptibility to obesity and metabolic dysfunction A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys326 polymorphic variant Dimerization and opposite base-dependent catalytic impairment of polymorphic S326C OGG1 glycosylase DNA Damage Response and Immune Defense: Links and Mechanisms Repair of oxidative DNA damage and cancer: recent progress in DNA base excision repair Cellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cells Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy DNA replication fidelity and cancer Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis.Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress.The role of mitochondrial DNA mutations in mammalian aging Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.Base excision repair of tandem modifications in a methylated CpG dinucleotide.No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis.Abnormality in Wnt signaling is causatively associated with oxidative stress-induced intestinal tumorigenesis in MUTYH-null mice.8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization.8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress Cigarette smoke induces nucleic-acid oxidation in lung fibroblasts 8-oxoguanine causes spontaneous de novo germline mutations in mice.8-Hydroxyguanine: From its discovery in 1983 to the present status.Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice.DNA repair gene polymorphisms and clinical outcome of patients with primary small cell carcinoma of the esophagus.Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1).Absence of the DNA repair enzyme human 8-oxoguanine glycosylase is associated with an aggressive breast cancer phenotype In Vitro Fluorogenic Real-Time Assay of the Repair of Oxidative DNA Damage.DNA sequence context effects on the glycosylase activity of human 8-oxoguanine DNA glycosylase.Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1.Mitochondrial DNA Repair through OGG1 Activity Attenuates Breast Cancer Progression and Metastasis 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions.DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice Monitoring repair of DNA damage in cell lines and human peripheral blood mononuclear cells DNA repair of oxidative DNA damage in human carcinogenesis: potential application for cancer risk assessment and prevention Regulation of DNA glycosylases and their role in limiting disease.Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of ogg1.Catalytic and DNA-binding properties of the human Ogg1 DNA N-glycosylase/AP lyase: biochemical exploration of H270, Q315 and F319, three amino acids of the 8-oxoguanine-binding pocket.Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine.Increased ROS generation in subsets of OGG1 knockout fibroblast cells

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Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

http://www.wikidata.org/entity/Q28180293

description

2003 nî lūn-bûn

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2003 թուականի Մարտին հրատարակուած գիտական յօդուած

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2003 թվականի մարտին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

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Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

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Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

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type

label

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

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Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

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Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

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prefLabel

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

@ast

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

@en

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

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Cancer Research

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Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

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Kunihiko Sakumi

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Masato Furuichi

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Mutsuo Sekiguchi

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Ping Xu

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Teruhisa Tsuzuki

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Yohei Tominaga

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Yusaku Nakabeppu

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scholarly article

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2003-03-01T00:00:00Z

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12615700

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