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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

http://www.wikidata.org/entity/Q36711322

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DNA Damage Response and Immune Defense: Links and Mechanisms Gut Microbiota Imbalance and Base Excision Repair Dynamics in Colon Cancer Epigenetic regulation of DNA repair machinery in Helicobacter pylori-induced gastric carcinogenesis Cancer heterogeneity--a multifaceted view DNA Damage and Pulmonary Hypertension At the Bench: Helicobacter pylori, dysregulated host responses, DNA damage, and gastric cancer Base excision repair and cancer Impact of Conformational Heterogeneity of OxoG Lesions and Their Pairing Partners on Bypass Fidelity by Y Family Polymerases Searching for DNA Lesions: Structural Evidence for Lower- and Higher-Affinity DNA Binding Conformations of Human Alkyladenine DNA Glycosylase Binary complex crystal structure of DNA polymerase reveals multiple conformations of the templating 8-oxoguanine lesion Structural Basis for Promutagenicity of 8-Halogenated Guanine Immunity, Inflammation, and Cancer DNA Damage: From Chronic Inflammation to Age-Related Deterioration The effect of environmental chemicals on the tumor microenvironment Base excision repair Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer Macrophage diversity enhances tumor progression and metastasis Oxidative stress, inflammation, and cancer: how are they linked?Helicobacter pylori and gastric cancer: Indian enigma.A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine.Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways.Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis.Gastric Helicobacter pylori infection associates with an increased risk of colorectal polyps in African Americans.Helminth co-infection in Helicobacter pylori infected INS-GAS mice attenuates gastric premalignant lesions of epithelial dysplasia and glandular atrophy and preserves colonization resistance of the stomach to lower bowel microbiota Inflammation and oncogenesis: a vicious connection.The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis.Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation.Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression.The mutator phenotype in cancer: molecular mechanisms and targeting strategies Microbiota, Inflammation and Colorectal Cancer.The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer.The Impact of Gut Microbiota on Gender-Specific Differences in Immunity.PRL-3 promotes telomere deprotection and chromosomal instability.Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models.Adenoma formation following limited ablation of p120-catenin in the mouse intestine.Repair of endogenous DNA base lesions modulate lifespan in mice RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects Mutagenic potency of Helicobacter pylori in the gastric mucosa of mice is determined by sex and duration of infection.

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P2860

DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

http://www.wikidata.org/entity/Q36711322

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2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

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Journal of Clinical Investigation

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DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

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Arlin B Rogers

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Barry H Rickman

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Bo Pang

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Catherine A Moroski-Erkul

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Chung-Wei Lee

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David B Schauer

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Diana Borenshtein

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James M Bugni

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Jose L McFaline

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Leona D Samson

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P2860

Inflammation and cancer

Inflammation, atrophy, and gastric cancer

Pathogenesis of Helicobacter pylori infection

Global cancer statistics, 2002

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

DNA repair activity for oxidative damage and risk of lung cancer

The global health burden of infection-associated cancers in the year 2002

The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats

The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system

Nuclear factor-kappaB in cancer development and progression

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2516-2525

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10.1172/JCI35073

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118

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18521188

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