Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human platelets
about
P2Y12 receptor-mediated potentiation of thrombin-induced thromboxane A2 generation in platelets occurs through regulation of Erk1/2 activationThrombin and vascular inflammationAn important role of the SRC family kinase Lyn in stimulating platelet granule secretionEvaluation of [3-(1-methyl-1H-indol-3-yl-methylene)-2-oxo-2, 3-dihydro-1H-indole-5-sulfonamide] (OXSI-2), as a Syk-selective inhibitor in platelets.Metalloproteolytic receptor shedding…platelets "acting their age".Syk Activity Is Dispensable for Platelet GP1b-IX-V Signaling.Evaluation of the physiological significance of botrocetin/ von Willebrand factor in vitro signaling.20-Hydroxyeicosatetraenoic acid involved in endothelial activation and thrombosis.Signaling during platelet adhesion and activationC-type lectin like receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets.Negative regulation of Gq-mediated pathways in platelets by G(12/13) pathways through Fyn kinase.Echicetin coated polystyrene beads: a novel tool to investigate GPIb-specific platelet activation and aggregationRegulation of the tumor suppressor FOXO3 by the thromboxane-A2 receptors in urothelial cancerBruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo.Protein kinase C isoform ε negatively regulates ADP-induced calcium mobilization and thromboxane generation in platelets.Flavonoids inhibit the platelet TxA(2) signalling pathway and antagonize TxA(2) receptors (TP) in platelets and smooth muscle cells.The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activationThe Src family kinases and protein kinase C synergize to mediate Gq-dependent platelet activation.Dual Roles of Quercetin in Platelets: Phosphoinositide-3-Kinase and MAP Kinases Inhibition, and cAMP-Dependent Vasodilator-Stimulated Phosphoprotein StimulationA functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complexSrc family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.Chlorin e6 Prevents ADP-Induced Platelet Aggregation by Decreasing PI3K-Akt Phosphorylation and Promoting cAMP Production.Impaired activation of platelets lacking protein kinase C-theta isoformp21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear.P2Y12 receptor: platelet thrombus formation and medical interventions.Of von Willebrand factor and platelets.Lovastatin corrects ERK pathway hyperactivation in fragile X syndrome: potential of platelet's signaling cascades as new outcome measures in clinical trials.New Concepts and Mechanisms of Platelet Activation Signaling.Update on the role of endothelial cells in trauma.Arachidonic acid depletion extends survival of cold-stored platelets by interfering with the [glycoprotein Ibα--14-3-3ζ] association.Regulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets.G-protein-gated inwardly rectifying potassium channels regulate ADP-induced cPLA2 activity in platelets through Src family kinases.The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation.Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β.Lighting up kinase action in platelets.Platelets as a surrogate disease model of neurodevelopmental disorders: Insights from Fragile X Syndrome.Extracellular signal-regulated kinase 5 associates with casein kinase II to regulate GPIb-IX-mediated platelet activation via the PTEN/PI3K/Akt pathway.Mechanism of anti-platelet activity of Oligoporus tephroleucus oligoporin A: involvement of extracellular signal-regulated kinase phosphorylation and cyclic nucleotide elevation.PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway.Ristocetin induces phosphorylated-HSP27 (HSPB1) release from the platelets of type 2 DM patients: Anti-platelet agent-effect on the release.
P2860
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P2860
Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human platelets
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Src family kinase-mediated and ...... activation in human platelets
@ast
Src family kinase-mediated and ...... activation in human platelets
@en
Src family kinase-mediated and ...... activation in human platelets
@nl
type
label
Src family kinase-mediated and ...... activation in human platelets
@ast
Src family kinase-mediated and ...... activation in human platelets
@en
Src family kinase-mediated and ...... activation in human platelets
@nl
prefLabel
Src family kinase-mediated and ...... activation in human platelets
@ast
Src family kinase-mediated and ...... activation in human platelets
@en
Src family kinase-mediated and ...... activation in human platelets
@nl
P2093
P2860
P1433
P1476
Src family kinase-mediated and ...... activation in human platelets
@en
P2093
Analia Garcia
Robert T Dorsam
Satya P Kunapuli
Todd M Quinton
P2860
P304
P356
10.1182/BLOOD-2005-05-1933
P407
P577
2005-11-15T00:00:00Z