Characterization and comparative analysis of the EGLN gene family
about
Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygenRegulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive elementBiochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor.A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasisSuppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitinationHIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxiaHypoxia-inducible factor-1alpha polymorphisms and TSC1/2 mutations are complementary in head and neck cancersThe active site of an algal prolyl 4-hydroxylase has a large structural plasticityDisruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activityThe novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3)HIF hydroxylation and cellular oxygen sensing.Falkor, a novel cell growth regulator isolated by a functional genetic screen.Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases.A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinerySrc activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin productionControl of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar.The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling.Human high-altitude adaptation: forward genetics meets the HIF pathway.Molecular characterization and mRNA expression of two key enzymes of hypoxia-sensing pathways in eastern oysters Crassostrea virginica (Gmelin): hypoxia-inducible factor α (HIF-α) and HIF-prolyl hydroxylase (PHD).HIF hydroxylation and the mammalian oxygen-sensing pathwayPartial depletion of yolk during zebrafish embryogenesis changes the dynamics of methionine cycle and metabolic genesChenodeoxycholic Acid Reduces Hypoxia Inducible Factor-1α Protein and Its Target Genes.Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.HIF1 and oxygen sensing in the brain.Redox regulation of the hypoxia-inducible factor.Prolyl hydroxylase domain protein 2 (PHD2) binds a Pro-Xaa-Leu-Glu motif, linking it to the heat shock protein 90 pathwayHypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress.Genetically heterogeneous origins of idiopathic erythrocytosis.HIF-independent role of prolyl hydroxylases in the cellular response to amino acidsThe Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.The role of HIF prolyl hydroxylases in tumour growth.Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase.Hypoxia inducible factor-1: its potential role in cerebral ischemia.HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression.EGLN3 prolyl hydroxylase regulates skeletal muscle differentiation and myogenin protein stability.Analysis of the hypoxia-sensing pathway in Drosophila melanogaster.Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.The expression profiles of miRNA-mRNA of early response in genetically improved farmed tilapia (Oreochromis niloticus) liver by acute heat stress.
P2860
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P2860
Characterization and comparative analysis of the EGLN gene family
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Characterization and comparative analysis of the EGLN gene family
@ast
Characterization and comparative analysis of the EGLN gene family
@en
Characterization and comparative analysis of the EGLN gene family
@nl
type
label
Characterization and comparative analysis of the EGLN gene family
@ast
Characterization and comparative analysis of the EGLN gene family
@en
Characterization and comparative analysis of the EGLN gene family
@nl
prefLabel
Characterization and comparative analysis of the EGLN gene family
@ast
Characterization and comparative analysis of the EGLN gene family
@en
Characterization and comparative analysis of the EGLN gene family
@nl
P1433
P1476
Characterization and comparative analysis of the EGLN gene family
@en
P2093
M S Taylor
P304
P356
10.1016/S0378-1119(01)00633-3
P407
P577
2001-09-05T00:00:00Z