Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling - Wikidata - wikimedia - TriplyDB

Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling

Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling

http://www.wikidata.org/entity/Q28189437

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Type I PIPK-alpha regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alpha Genomic tagging of endogenous type IIbeta phosphatidylinositol 5-phosphate 4-kinase in DT40 cells reveals a nuclear localisation Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation PtdIns(4,5)P2-mediated cell signaling: emerging principles and PTEN as a paradigm for regulatory mechanism Lipid kinases as therapeutic targets for chronic pain Regulation of platelet plug formation by phosphoinositide metabolism PIP kinases define PI4,5P₂signaling specificity by association with effectors Emerging roles of PtdIns(4,5)P2--beyond the plasma membrane Phosphoinositides are essential coactivators for p21-activated kinase 1 Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins.Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.Immunostaining evidence for PI(4,5)P2 localization at the leading edge of chemoattractant-stimulated HL-60 cells.Phosphatidylinositol 4-phosphate 5-kinase alpha (PIPKα) regulates neuronal microtubule depolymerase kinesin, KIF2A and suppresses elongation of axon branches.Nuclear phosphoinositides: a signaling enigma wrapped in a compartmental conundrum.Type I phosphatidylinositol phosphate kinase beta regulates focal adhesion disassembly by promoting beta1 integrin endocytosis Impact of engagement of FcepsilonRI and CC chemokine receptor 1 on mast cell activation and motility.PIP5KI gamma is required for cardiovascular and neuronal development Cytoskeletal regulation: rich in lipids.Type I gamma phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration Lipid rafts and regulation of the cytoskeleton during T cell activation.Phosphatidylinositol-4-phosphate 5-kinase isoforms exhibit acyl chain selectivity for both substrate and lipid activator Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.Phospholipase D signaling: orchestration by PIP2 and small GTPases.A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family.Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation.PI3K p110β isoform synergizes with JNK in the regulation of glioblastoma cell proliferation and migration through Akt and FAK inhibition.Out, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis.Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation.Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting.HECTD1 controls the protein level of IQGAP1 to regulate the dynamics of adhesive structures.Regulation of PIP5K activity by Arf6 and its physiological significance.The multifaceted role of PIP2 in leukocyte biology.Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases.Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells Phosphatidylinositol-4-phosphate 5-Kinase 1α Modulates Ribosomal RNA Gene Silencing through Its Interaction with Histone H3 Lysine 9 Trimethylation and Heterochromatin Protein HP1-α.The intracellular localisation and mobility of Type Igamma phosphatidylinositol 4P 5-kinase splice variants.Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42.

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P2860

Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling

http://www.wikidata.org/entity/Q28189437

description

2003 nî lūn-bûn

@nan

2003 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

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2003年论文

@wuu

name

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@ast

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@en

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@nl

type

label

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@ast

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@en

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@nl

prefLabel

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@ast

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@en

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Membrane ruffling requires coo ...... phate kinase and Rac signaling

@en

P2093

Matthew W Bunce

http://www.w3.org/2001/XMLSchema#string

Michelle L Wojtasiak

http://www.w3.org/2001/XMLSchema#string

Renee L Doughman

http://www.w3.org/2001/XMLSchema#string

P2860

Localized Rac activation dynamics visualized in living cells

Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors

Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

Rho GTPases and the actin cytoskeleton

Cell migration: a physically integrated molecular process

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Phosphatidylinositol-4-phosphate 5-kinase localized on the plasma membrane is essential for yeast cell morphogenesis.

MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae.

Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation

P304

23036-23045

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scholarly article

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1644125

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10.1074/JBC.M211397200

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P433

25

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278

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Ari J Firestone

Richard A. Anderson

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2003-04-06T00:00:00Z

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12682053

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