PIP5KI gamma is required for cardiovascular and neuronal development
about
IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.Phosphoinositides: tiny lipids with giant impact on cell regulationModeling anterior development in mice: diet as modulator of risk for neural tube defectsEarly Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin NetworkPIP kinases define PI4,5P₂signaling specificity by association with effectorsMethamphetamine preconditioning alters midbrain transcriptional responses to methamphetamine-induced injury in the rat striatumPhosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brainPlatelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesionNeural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinaseReduced phosphatidylinositol 4,5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisitionStrain-specific modifier genes governing craniofacial phenotypes.Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.Loss of phosphatidylinositol 4-kinase 2alpha activity causes late onset degeneration of spinal cord axonsDownregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis.Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain.Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects.Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer.Phosphatidylinositol 4,5-bisphosphate: targeted production and signalingGenetics and development of neural tube defects.EZH2 regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signalingAn integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma.PIP2 signaling, an integrator of cell polarity and vesicle trafficking in directionally migrating cells.Mutations in phosphoinositide metabolizing enzymes and human disease.Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis.Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation.Out, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis.Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis.Mechanism of substrate specificity of phosphatidylinositol phosphate kinases.Clathrin regulates the association of PIPKIgamma661 with the AP-2 adaptor beta2 appendage.Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting.Mouse as a model for multifactorial inheritance of neural tube defects.Phosphatidylinositol 4-kinases and PI4P metabolism in the nervous system: roles in psychiatric and neurological diseases.The actin-driven spatiotemporal organization of T-cell signaling at the system scale.IQGAP1 is a phosphoinositide effector and kinase scaffoldIntegrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis.The lipid kinase PIP5K1C regulates pain signaling and sensitizationIntegrin-induced PIP5K1C kinase polarization regulates neutrophil polarization, directionality, and in vivo infiltration.Smurf1 regulates lung cancer cell growth and migration through interaction with and ubiquitination of PIPKIγ.[EXPRESS] Conditional deletion of Pip5k1c in sensory ganglia and effects on nociception and inflammatory sensitization.Myo-inositol soft gel capsules may prevent the risk of coffee-induced neural tube defects.
P2860
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P2860
PIP5KI gamma is required for cardiovascular and neuronal development
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
PIP5KI gamma is required for cardiovascular and neuronal development
@ast
PIP5KI gamma is required for cardiovascular and neuronal development
@en
PIP5KI gamma is required for cardiovascular and neuronal development
@nl
type
label
PIP5KI gamma is required for cardiovascular and neuronal development
@ast
PIP5KI gamma is required for cardiovascular and neuronal development
@en
PIP5KI gamma is required for cardiovascular and neuronal development
@nl
prefLabel
PIP5KI gamma is required for cardiovascular and neuronal development
@ast
PIP5KI gamma is required for cardiovascular and neuronal development
@en
PIP5KI gamma is required for cardiovascular and neuronal development
@nl
P2093
P2860
P356
P1476
PIP5KI gamma is required for cardiovascular and neuronal development
@en
P2093
Charles S Abrams
Edward E Morrisey
Jeffrey A Golden
Lurong Lian
Yanfeng Wang
P2860
P304
11748-11753
P356
10.1073/PNAS.0700019104
P407
P577
2007-07-03T00:00:00Z