PIP5KI gamma is required for cardiovascular and neuronal development - Wikidata - wikimedia - TriplyDB

PIP5KI gamma is required for cardiovascular and neuronal development

PIP5KI gamma is required for cardiovascular and neuronal development

http://www.wikidata.org/entity/Q34645669

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IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.Phosphoinositides: tiny lipids with giant impact on cell regulation Modeling anterior development in mice: diet as modulator of risk for neural tube defects Early Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin Network PIP kinases define PI4,5P₂signaling specificity by association with effectors Methamphetamine preconditioning alters midbrain transcriptional responses to methamphetamine-induced injury in the rat striatum Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain Platelets lacking PIP5KIγ have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase Reduced phosphatidylinositol 4,5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisition Strain-specific modifier genes governing craniofacial phenotypes.Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.Loss of phosphatidylinositol 4-kinase 2alpha activity causes late onset degeneration of spinal cord axons Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis.Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain.Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects.Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer.Phosphatidylinositol 4,5-bisphosphate: targeted production and signaling Genetics and development of neural tube defects.EZH2 regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signaling An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma.PIP2 signaling, an integrator of cell polarity and vesicle trafficking in directionally migrating cells.Mutations in phosphoinositide metabolizing enzymes and human disease.Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis.Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation.Out, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis.Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis.Mechanism of substrate specificity of phosphatidylinositol phosphate kinases.Clathrin regulates the association of PIPKIgamma661 with the AP-2 adaptor beta2 appendage.Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting.Mouse as a model for multifactorial inheritance of neural tube defects.Phosphatidylinositol 4-kinases and PI4P metabolism in the nervous system: roles in psychiatric and neurological diseases.The actin-driven spatiotemporal organization of T-cell signaling at the system scale.IQGAP1 is a phosphoinositide effector and kinase scaffold Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis.The lipid kinase PIP5K1C regulates pain signaling and sensitization Integrin-induced PIP5K1C kinase polarization regulates neutrophil polarization, directionality, and in vivo infiltration.Smurf1 regulates lung cancer cell growth and migration through interaction with and ubiquitination of PIPKIγ.[EXPRESS] Conditional deletion of Pip5k1c in sensory ganglia and effects on nociception and inflammatory sensitization.Myo-inositol soft gel capsules may prevent the risk of coffee-induced neural tube defects.

P2860

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P2860

PIP5KI gamma is required for cardiovascular and neuronal development

http://www.wikidata.org/entity/Q34645669

description

2007 nî lūn-bûn

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2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

PIP5KI gamma is required for cardiovascular and neuronal development

@ast

PIP5KI gamma is required for cardiovascular and neuronal development

@en

PIP5KI gamma is required for cardiovascular and neuronal development

@nl

type

label

PIP5KI gamma is required for cardiovascular and neuronal development

@ast

PIP5KI gamma is required for cardiovascular and neuronal development

@en

PIP5KI gamma is required for cardiovascular and neuronal development

@nl

prefLabel

PIP5KI gamma is required for cardiovascular and neuronal development

@ast

PIP5KI gamma is required for cardiovascular and neuronal development

@en

PIP5KI gamma is required for cardiovascular and neuronal development

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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PIP5KI gamma is required for cardiovascular and neuronal development

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P2093

Charles S Abrams

http://www.w3.org/2001/XMLSchema#string

Edward E Morrisey

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Golden

http://www.w3.org/2001/XMLSchema#string

Lurong Lian

http://www.w3.org/2001/XMLSchema#string

Yanfeng Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family

Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin

Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling

PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapse

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate

Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

Developmental defects in mouse embryos lacking N-cadherin

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104

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17609388

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Aparato circulatorio

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1913884

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