Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints
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sameAs
Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.Snaps and mends: DNA breaks and chromosomal translocationsComputational tools for understanding sequence variability in recombination signalsIn vivo reinsertion of excised episomes by the V(D)J recombinase: a potential threat to genomic stability.Phosphorylation site analysis of the anti-inflammatory and mRNA-destabilizing protein tristetraprolin.HMGB1/2 can target DNA for illegitimate cleavage by the RAG1/2 complex.Mechanisms of chromosomal rearrangement in the human genomeNon-consensus heptamer sequences destabilize the RAG post-cleavage complex, making ends available to alternative DNA repair pathways.Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humansOrigins of chromosome translocations in childhood leukaemia.The molecular basis and biological significance of VH replacement.Illegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy.V(D)J recombinase-mediated processing of coding junctions at cryptic recombination signal sequences in peripheral T cells during human development.Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequencesTristetraprolin regulation of interleukin-22 productionChromosomal reinsertion of broken RSS ends during T cell development.Genomic EWS-FLI1 fusion sequences in Ewing sarcoma resemble breakpoint characteristics of immature lymphoid malignancies.The cellular etiology of chromosome translocations.Mechanisms of leukemia translocationsTwo pathways of costimulation through CD28.How does DNA break during chromosomal translocations?The cardinal role of the phospholipase A(2)/cyclooxygenase-2/prostaglandin E synthase/prostaglandin E(2) (PCPP) axis in inflammostasis.Mechanisms and impacts of chromosomal translocations in cancers.Sequence and structural basis for chromosomal fragility during translocations in cancer.Role of recombination activating genes in the generation of antigen receptor diversity and beyond.Breakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia.Histone methylation and V(D)J recombination.The structure-specific nicking of small heteroduplexes by the RAG complex: implications for lymphoid chromosomal translocations.A non-B DNA can replace heptamer of V(D)J recombination when present along with a nonamer: implications in chromosomal translocations and cancer.mRNA openers and closers: modulating AU-rich element-controlled mRNA stability by a molecular switch in mRNA secondary structure.Mechanisms of human lymphoid chromosomal translocations.V(D)J-mediated translocations in lymphoid neoplasms: a functional assessment of genomic instability by cryptic sites.Mechanism of fragility at BCL2 gene minor breakpoint cluster region during t(14;18) chromosomal translocation.Mechanistic basis for RAG discrimination between recombination sites and the off-target sites of human lymphomas.Cytosines, but not purines, determine recombination activating gene (RAG)-induced breaks on heteroduplex DNA structures: implications for genomic instability.Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells.HIV integrase inhibitor, Elvitegravir, impairs RAG functions and inhibits V(D)J recombination.Evidence for a triplex DNA conformation at the bcl-2 major breakpoint region of the t(14;18) translocation.RAG Recombinase as a Selective Pressure for Genome EvolutionA Novel Quantitative Fluorescent Reporter Assay for RAG Targets and RAG Activity.
P2860
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P2860
Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@ast
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@en
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@nl
type
label
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@ast
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@en
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@nl
prefLabel
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@ast
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@en
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@nl
P2093
P2860
P356
P1476
Analysis of the V(D)J recombin ...... omal translocation breakpoints
@en
P2093
I R Kirsch
M R Lieber
S C Raghavan
P2860
P304
P356
10.1074/JBC.M103797200
P407
P577
2001-08-03T00:00:00Z