Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints.
about
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathwayDistinct requirements for Ku in N nucleotide addition at V(D)J- and non-V(D)J-generated double-strand breaksAnalysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpointsTerminal deoxynucleotidyl transferase: the story of a misguided DNA polymerasebcl-2 translocation in Japanese B cell lymphoma: novel bcl-2 translocation with immunoglobulin heavy chain diversity segment.Rearrangement by inversion of a T-cell receptor delta variable region gene located 3' of the delta constant region geneNucleotide pool imbalance and adenosine deaminase deficiency induce alterations of N-region insertions during V(D)J recombination.Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination.Ku80 is required for addition of N nucleotides to V(D)J recombination junctions by terminal deoxynucleotidyl transferaseA Rad50-dependent pathway of DNA repair is deficient in Fanconi anemia fibroblastsCharacterization of the immunoglobulin heavy chain complementarity determining region (CDR)-III sequences from human B cell precursor acute lymphoblastic leukemia cells.CDR3 sequence motifs shared by oligoclonal rheumatoid arthritis synovial T cells. Evidence for an antigen-driven response.A transgenic mouse that expresses a diversity of human sequence heavy and light chain immunoglobulinsComparison of junctional diversity in the neonatal and adult immunoglobulin repertoires.Junctional sequences of fetal T cell receptor beta chains have few N regions.Severe combined immunodeficiency (SCID) in man: B cell-negative (B-) SCID patients exhibit an irregular recombination pattern at the JH locus.The chromosome translocation (11;14)(p13;q11) associated with T cell acute leukemia. Asymmetric diversification of the translocational junctions.Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences.Restricted immunoglobulin junctional diversity in neonatal B cells results from developmental selection rather than homology-based V(D)J joiningJunctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity.Functional characterization of B lymphocytes generated in vitro from embryonic stem cells.Assessing the pathogenic potential of the V(D)J recombinase by interlocus immunoglobulin light-chain gene rearrangementKu86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products.Abnormal deletions in the T-cell receptor delta locus of mouse thymocytes.P nucleotides in V(D)J recombination: a fine-structure analysis.Characterization of broken DNA molecules associated with V(D)J recombination.Biased T-cell receptor delta element recombination in scid thymocytes.Wild-type V(D)J recombination in scid pre-B cellsThe (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinaseMouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain.Effects of DNA end configuration on XRCC4-DNA ligase IV and its stimulation of Artemis activity.Detecting variable (V), diversity (D) and joining (J) gene segment recombination using a two-colour fluorescence system.The ATM Kinase Restrains Joining of Both VDJ Signal and Coding Ends.CDR3 motif generation and selection in the BV19-utilizing subset of the human CD8 T cell repertoire.A biochemically defined system for coding joint formation in V(D)J recombination.Nucleotide deletion and P addition in V(D)J recombination: a determinant role of the coding-end sequence.Chromosome 11q23 abnormalities in leukaemia.B-cell precursors differentiated from cord blood CD34+ cells are more immature than those derived from granulocyte colony-stimulating factor-mobilized peripheral blood CD34+ cells.The SCID mouse: relevance as an animal model system for studying human disease.Excision products of the T cell receptor gene support a progressive rearrangement model of the alpha/delta locus.
P2860
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P2860
Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints.
description
1988 nî lūn-bûn
@nan
1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Lymphoid V(D)J recombination: ...... ints as well as coding joints.
@ast
Lymphoid V(D)J recombination: ...... ints as well as coding joints.
@en
type
label
Lymphoid V(D)J recombination: ...... ints as well as coding joints.
@ast
Lymphoid V(D)J recombination: ...... ints as well as coding joints.
@en
prefLabel
Lymphoid V(D)J recombination: ...... ints as well as coding joints.
@ast
Lymphoid V(D)J recombination: ...... ints as well as coding joints.
@en
P2093
P2860
P356
P1476
Lymphoid V(D)J recombination: ...... ints as well as coding joints.
@en
P2093
P2860
P304
P356
10.1073/PNAS.85.22.8588
P407
P577
1988-11-01T00:00:00Z