Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1 - Wikidata - wikimedia - TriplyDB

Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1

Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1

http://www.wikidata.org/entity/Q28204964

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TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1 The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks.The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor The Drosophila splicing factor PSI is phosphorylated by casein kinase II and tousled-like kinase Mitotic crisis: the unmasking of a novel role for RPA DNA damage response and repair data with pharmacological modulators of Tousled.TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1.Replication licensing and the DNA damage checkpoint.ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy.Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit.Checking on DNA damage in S phase.Centrosomal Che-1 protein is involved in the regulation of mitosis and DNA damage response by mediating pericentrin (PCNT)-dependent Chk1 protein localization The C. elegans Tousled-like kinase contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase.Replicating chromatin: a tale of histones.Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response.Purification, crystallization and preliminary X-ray diffraction analysis of the kinase domain of human tousled-like kinase 2.Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication.Beyond ATM: the protein kinase landscape of the DNA damage response.The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression.Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest.Tousled-mediated activation of Aurora B kinase does not require Tousled kinase activity in vivo.The Tousled-Like Kinases as Guardians of Genome Integrity Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1.Tousled-like kinase 1 is a negative regulator of core transcription factors in murine embryonic stem cells.High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer.Molecular basis of Tousled-Like Kinase 2 activation.Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors

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Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1

http://www.wikidata.org/entity/Q28204964

description

2003 nî lūn-bûn

@nan

2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

@ast

Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

@en

Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

@nl

type

label

Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

@ast

Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

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Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

@nl

prefLabel

Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

@ast

Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

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Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

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Suppression of Tousled-like ki ...... ck requires ATM, NBS1 and Chk1

@en

P2093

Bin-Bing Zhou

http://www.w3.org/2001/XMLSchema#string

Darren R Krause

http://www.w3.org/2001/XMLSchema#string

Herman H W Sillje

http://www.w3.org/2001/XMLSchema#string

Jyoti C Jonnalagadda

http://www.w3.org/2001/XMLSchema#string

Kumkum Khanna

http://www.w3.org/2001/XMLSchema#string

Magtouf H Gatei

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies

Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach.

Radiosensitivity in ataxia-telangiectasia: a new explanation.

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10.1038/SJ.ONC.1206691

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38

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22

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12955071

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