PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis
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The Homer family proteinsPIKE-A is required for prolactin-mediated STAT5a activation in mammary gland developmentThe association of phosphoinositide 3-kinase enhancer A with hepatic insulin receptor enhances its kinase activityNetrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5BNeuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidasePhosphoinositol lipids bind to phosphatidylinositol 3 (PI3)-kinase enhancer GTPase and mediate its stimulatory effect on PI3-kinase and Akt signalingsPIKE-A is amplified in human cancers and prevents apoptosis by up-regulating AktGroup 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and diseasePIKE GTPase signaling and functionDysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of AutismThe roles of PIKE in tumorigenesisIncreased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.The PIKE homolog Centaurin gamma regulates developmental timing in DrosophilaPIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasionSemiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometryPIKE-mediated PI3-kinase activity is required for AMPA receptor surface expressionRegulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice.From FMRP function to potential therapies for fragile X syndrome.Metabotropic glutamate receptors: from the workbench to the bedside.Preclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.Homers regulate drug-induced neuroplasticity: implications for addictionRoles of PI3K and JAK pathways in viability of retinal ganglion cells after acute elevation of intraocular pressure in rats with different autoimmune backgrounds.A PI3-kinase-mediated negative feedback regulates neuronal excitability.Akt-dependent cell size regulation by the adhesion molecule on glia occurs independently of phosphatidylinositol 3-kinase and Rheb signaling.Vitamin D, Homocysteine, and Folate in Subcortical Vascular Dementia and Alzheimer DementiaDeficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance.Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismSynergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cellsLocation-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5.Albuminuria and glomerular damage in mice lacking the metabotropic glutamate receptor 1.Akt-phosphorylated PIKE-A inhibits UNC5B-induced apoptosis in cancer cell lines in a p53-dependent manner.Frontier of epilepsy research - mTOR signaling pathway.Novel candidate key drivers in the integrative network of genes, microRNAs, methylations, and copy number variations in squamous cell lung carcinoma.The gene expression response of chronic lymphocytic leukemia cells to IL-4 is specific, depends on ZAP-70 status and is differentially affected by an NFκB inhibitor.Selective role of the catalytic PI3K subunit p110β in impaired higher order cognition in fragile X syndrome.Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond.The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation.An emerging role for the Mammalian target of rapamycin in "pathological" protein translation: relevance to cocaine addiction.Erythropoietin on a tightrope: balancing neuronal and vascular protection between intrinsic and extrinsic pathways.
P2860
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P2860
PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@ast
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@en
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@nl
type
label
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@ast
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@en
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@nl
prefLabel
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@ast
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@en
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@nl
P2093
P2860
P3181
P356
P1433
P1476
PI3 kinase enhancer-Homer comp ...... preventing neuronal apoptosis
@en
P2093
Daniel Kalman
Eiichiro Nagata
Honglian Huang
Jee-Yin Ahn
Jiancheng Tu
Judith A Kapp
Keqiang Ye
Paul F Worley
P2860
P2888
P304
P3181
P356
10.1038/NN1134
P407
P577
2003-11-01T00:00:00Z
P6179
1038685224