Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance. - Wikidata - wikimedia - TriplyDB

Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance.

Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance.

http://www.wikidata.org/entity/Q33750723

about

The association of phosphoinositide 3-kinase enhancer A with hepatic insulin receptor enhances its kinase activity The roles of PIKE in tumorigenesis The PIKE homolog Centaurin gamma regulates developmental timing in Drosophila Fyn regulates adipogenesis by promoting PIKE-A/STAT5a interaction Frontier of epilepsy research - mTOR signaling pathway.Activation of muscular TrkB by its small molecular agonist 7,8-dihydroxyflavone sex-dependently regulates energy metabolism in diet-induced obese mice.Voluntary physical activity prevents insulin resistance in a tissue specific manner Loss of TDAG51 results in mature-onset obesity, hepatic steatosis, and insulin resistance by regulating lipogenesis.Phosphoinositide 3-kinase enhancer regulates neuronal dendritogenesis and survival in neocortex Essential role of PIKE GTPases in neuronal protection against excitotoxic insults Fyn is a redox sensor involved in solar ultraviolet light-induced signal transduction in skin carcinogenesis.Phosphoinositide 3-kinase enhancer (PIKE) in the brain: is it simply a phosphoinositide 3-kinase/Akt enhancer?PIKE is essential for oligodendroglia development and CNS myelination.Genome-wide analysis identifies colonic genes differentially associated with serum leptin and insulin concentrations in C57BL/6J mice fed a high-fat diet.What we have learnt about PIKE from the knockout mice.Tumor Necrosis Factor-α Promotes Phosphoinositide 3-Kinase Enhancer A and AMP-Activated Protein Kinase Interaction to Suppress Lipid Oxidation in Skeletal Muscle.Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity.Alteration of FXR phosphorylation and sumoylation in liver in the development of adult catch-up growth.α-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation.Dietary strawberry powder reduces blood glucose concentrations in obese and lean C57BL/6 mice, and selectively lowers plasma C-reactive protein in lean mice.

P2860

Q24309086-06113229-8F9A-41E1-BB23-0F8A4559E007 Q27023876-9027E5B1-1FA8-4092-AFCA-8EE899EA72C1 Q27332339-C2B1F62B-904B-4406-9764-09E94151107D Q28590056-CED95096-227F-42D3-8DD3-F0F434A22AD9 Q35014198-2F7BC479-5AE8-412B-AC06-30C5AF82C5DC Q35205542-209BA220-EC5C-4465-817F-F9ED8E5F8DA2 Q35363510-0F3C5AEB-421C-4BB7-886F-655639889D89 Q36477235-5896FB4B-06A5-4B4E-8D43-522359570D3A Q36551237-1EF40492-6FB8-407E-90ED-A5E233AECBDA Q36575969-73F5034F-D35D-4EF9-8686-019FB005DF0D Q37026588-3B4CB3D0-F421-43F4-B490-E8A24F977022 Q37139942-2FE2D42E-E6AA-4FEE-9549-9EA588E133EF Q37571127-B8BEDEF9-EACF-4E03-99FF-583F9DCAC77F Q37629433-0474FE4A-991C-4A11-815A-A4CEFD648EA8 Q37946372-B750AF4A-A067-4F05-8368-52141342D025 Q38839545-D75C2A9F-6BE2-4B2D-A2DC-5392CC27FF23 Q39739729-7096292B-AC0F-4715-BE69-C80D497E487F Q42292525-F8BC74B2-DD53-4698-BA9C-BE8DC326D869 Q42323946-A1005F36-AEDF-46DE-8E7B-D7DF6D1AE307 Q46682226-64610A4C-85CB-4076-B466-CC4138A1F3CF

P2860

Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance.

http://www.wikidata.org/entity/Q33750723

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Deficiency of phosphoinositide ...... besity and insulin resistance.

@ast

Deficiency of phosphoinositide ...... besity and insulin resistance.

@en

type

label

Deficiency of phosphoinositide ...... besity and insulin resistance.

@ast

Deficiency of phosphoinositide ...... besity and insulin resistance.

@en

prefLabel

Deficiency of phosphoinositide ...... besity and insulin resistance.

@ast

Deficiency of phosphoinositide ...... besity and insulin resistance.

@en

P1433

Q33750723-DA7554A0-816F-4B05-9007-016266C9D80F

P1476

Q33750723-00DB0201-CC4B-4452-83BE-1D6B5F235654

P2093

Q33750723-2C663084-4AB1-429F-BB2E-A9A9D888C4EB

Q33750723-79605072-F6CE-48B5-BA53-C82B8DCCD55D

Q33750723-B8A97144-E44E-42CA-889B-8CB1C3A75783

Q33750723-BCF930CC-F34E-47D5-943C-9A18E6138652

Q33750723-E96B409F-E552-455A-9206-42D3FE685D9E

Q33750723-F456050C-FCA4-43B4-B3CD-DA0D41B15DE1

Q33750723-FA6AB718-C206-4247-A709-360152F0E31B

P2860

Q33750723-03A212EA-DBC6-46B6-A1A6-1E2DD2F609C2

Q33750723-05E36E7E-56BC-4279-8BD0-782E454B87E2

Q33750723-0A9ACD92-F112-448B-BBF9-0165DAF4B768

Q33750723-196B7BC7-949D-42BE-8956-17246D870B58

Q33750723-1B5CDFDD-4C23-4BAA-ADBB-235481C9C7E8

Q33750723-1D6D2D44-1F12-495E-ABB4-9B9BA90F17A3

Q33750723-26A7CB40-24DF-4C66-A95E-84B04033CDD6

Q33750723-2B31D7BA-A51B-4972-A72E-95BE35E631BB

Q33750723-2CA4BB2E-BD8C-496D-BE16-452DAA127319

Q33750723-359D7EBA-4DA1-4AE4-9718-63268644121D

P304

Q33750723-DA337962-8A88-45D2-B1BC-913ECB1E600B

P31

Q33750723-F840A624-F483-42D8-A9D0-19964E575F8C

P356

Q33750723-D968F501-27FE-4D71-A741-226AC7364043

P407

Q33750723-FED8EA7E-93B0-48FB-BD6F-68DD7BB5EF4F

P433

Q33750723-8D29D756-582B-4932-88AA-F9D0680DA610

P478

Q33750723-A880C320-B28B-457D-8FC9-20FC84A8A3C9

P577

Q33750723-9DBC9997-7C3E-459C-9B72-A2CF5B9ECE26

P5875

Q33750723-522013F5-5993-4831-A342-B9337CFA7D3F

P698

Q33750723-CE9AB311-E15F-4068-B361-6BDF15F3FB94

P921

Q33750723-41F068EF-0240-4044-A478-D27CABA5E878

Q33750723-4B67775D-E59A-4BF8-AE13-64FF2008CF9B

P932

Q33750723-5D90412F-EA46-4027-B3BF-EC27461495DC

P356

P1433

P1476

Deficiency of phosphoinositide ...... besity and insulin resistance.

@en

P2093

Chi Bun Chan

http://www.w3.org/2001/XMLSchema#string

Dae Young Jung

http://www.w3.org/2001/XMLSchema#string

Hongbo R Luo

http://www.w3.org/2001/XMLSchema#string

Jason K Kim

http://www.w3.org/2001/XMLSchema#string

John Y Jun

http://www.w3.org/2001/XMLSchema#string

Keqiang Ye

http://www.w3.org/2001/XMLSchema#string

Xia Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N

Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins

PIKE-A is amplified in human cancers and prevents apoptosis by up-regulating Akt

Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor

PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE

PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion

Src-family tyrosine kinase fyn phosphorylates phosphatidylinositol 3-kinase enhancer-activating Akt, preventing its apoptotic cleavage and promoting cell survival

Peripheral effect of alpha-melanocyte-stimulating hormone on fatty acid oxidation in skeletal muscle

P304

883-893

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.2337/DB09-1404

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

59

http://www.w3.org/2001/XMLSchema#string

P577

2010-01-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

41000805

http://www.w3.org/2001/XMLSchema#string

P698

20068140

http://www.w3.org/2001/XMLSchema#string

P921

P932

2844836

http://www.w3.org/2001/XMLSchema#string