Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation - Wikidata - wikimedia - TriplyDB

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

http://www.wikidata.org/entity/Q28208407

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The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis A Complex Interplay between Wnt/β-Catenin Signalling and the Cell Cycle in the Adult Liver Phosphorylation of cyclin Y by CDK14 induces its ubiquitination and degradation FBXW7-mediated degradation of CCDC6 is impaired by ATM during DNA damage response in lung cancer cells Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7 HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression The ubiquitin-specific protease USP28 is required for MYC stability Quantitative proteomics identifies a Dab2/integrin module regulating cell migration MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7 Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase AKT/PKB signaling: navigating downstream SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae GSK-3 as potential target for therapeutic intervention in cancer Mitotic and mitogenic Wnt signalling Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase The Mck1 GSK-3 kinase inhibits the activity of Clb2-Cdk1 post-nuclear division SCFCdc4 enables mating type switching in yeast by cyclin-dependent kinase-mediated elimination of the Ash1 transcriptional repressor.Landscape of Pin1 in the cell cycle Function and regulation of cullin-RING ubiquitin ligases The SCF ubiquitin ligase: insights into a molecular machine Cyclins: roles in mitogenic signaling and oncogenic transformation The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles A hybrid model of mammalian cell cycle regulation Constitutive turnover of cyclin E by Cul3 maintains quiescence AS101 prevents diabetic nephropathy progression and mesangial cell dysfunction: regulation of the AKT downstream pathway The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation Regulation of protein stability by GSK3 mediated phosphorylation.GSK-3: Functional Insights from Cell Biology and Animal Models.Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels.A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.GSK-3 inhibitors induce chromosome instability.Activation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells.Turn It Down a Notch The negative cell cycle regulators, p27(Kip1), p18(Ink4c), and GSK-3, play critical role in maintaining quiescence of adult human pancreatic β-cells and restrict their ability to proliferate.Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways Multisite phosphorylation provides an effective and flexible mechanism for switch-like protein degradation.

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P2860

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

http://www.wikidata.org/entity/Q28208407

description

2003 nî lūn-bûn

@nan

2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

@ast

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

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Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

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type

label

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

@ast

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

@en

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

@nl

prefLabel

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

@ast

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

@en

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

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Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

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Andrew Bloecher

http://www.w3.org/2001/XMLSchema#string

Bruce E Clurman

http://www.w3.org/2001/XMLSchema#string

James M Roberts

http://www.w3.org/2001/XMLSchema#string

Jeffrey Singer

http://www.w3.org/2001/XMLSchema#string

Jonathan Grim

http://www.w3.org/2001/XMLSchema#string

Keith R Loeb

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Mark Gurien-West

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381-92

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10.1016/S1097-2765(03)00287-9

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phosphorylation