Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma
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Functional association between Wwox tumor suppressor protein and p73, a p53 homologFrequent downregulation and loss of WWOX gene expression in human hepatocellular carcinomaTargeted deletion of Wwox reveals a tumor suppressor functionWWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcomeCommon fragile sites: genomic hotspots of DNA damage and carcinogenesisWWOX, the common chromosomal fragile site, FRA16D, cancer geneA genome-wide association study identifies susceptibility variants for type 2 diabetes in Han ChineseA novel approach to simultaneously scan genes at fragile sitesNone-endoscopic Screening for Esophageal Squamous Cell Carcinoma- A Review.Single nucleotide polymorphism-based genome-wide chromosome copy change, loss of heterozygosity, and aneuploidy in Barrett's esophagus neoplastic progression.Molecular alterations in the tumor suppressor gene WWOX in oral leukoplakias.WWOX protein expression in normal human tissues.Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor statusWWOX gene restoration prevents lung cancer growth in vitro and in vivoLow levels of WWOX protein immunoexpression correlate with tumour grade and a less favourable outcome in patients with urinary bladder tumours.DNA instability at chromosomal fragile sites in cancerWWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear.Diverse effect of WWOX overexpression in HT29 and SW480 colon cancer cell lines.Oncosuppressor proteins of fragile sites are reduced in cervical cancer.Molecular analysis of WWOX expression correlation with proliferation and apoptosis in glioblastoma multiformeWWOX expression in colorectal cancer--a real-time quantitative RT-PCR study.Epigenetic and genetic alterations affect the WWOX gene in head and neck squamous cell carcinoma.Expression of WW domain-containing oxidoreductase WWOX in pterygiumGenetically engineered mouse models and human osteosarcoma.The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX.Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductaseHypermethylation-mediated reduction of WWOX expression in intraductal papillary mucinous neoplasms of the pancreas.Gene expression of WWOX, FHIT and p73 in acute lymphoblastic leukemiaFunctional genetic variant in the Kozak sequence of WW domain-containing oxidoreductase (WWOX) gene is associated with oral cancer risk.Common Chromosomal Fragile Site Gene WWOX in Metabolic Disorders and TumorsWWOX: a fragile tumor suppressor.WWOX, large common fragile site genes, and cancer.WWOX induces apoptosis and inhibits proliferation of human hepatoma cell line SMMC-7721.Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.Recurrent alterations of the WW domain containing oxidoreductase gene spanning the common fragile site FRA16D in multiple myeloma and monoclonal gammopathy of undetermined significance.Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas.Alternating expression levels of WWOX tumor suppressor and cancer-related genes in patients with bladder cancer.Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events.Tumor Suppressor Gene in Breast Cancer, a Historical Perspective and Future Directions
P2860
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P2860
Genetic alterations of the tumor suppressor gene WWOX in esophageal squamous cell carcinoma
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@ast
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@en
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@nl
type
label
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@ast
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@en
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@nl
prefLabel
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@ast
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@en
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@nl
P2093
P1433
P1476
Genetic alterations of the tum ...... hageal squamous cell carcinoma
@en
P2093
Francesco Trapasso
Koshi Mimori
Masaki Mori
Takeshi Shiraishi
Tamotsu Kuroki
P304
P407
P577
2002-04-15T00:00:00Z