Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
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Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor proteinCommon fragile sites: genomic hotspots of DNA damage and carcinogenesisTumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogasterTumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage ResponseWWOX, the chromosomal fragile site FRA16D spanning gene: its role in metabolism and contribution to cancerPleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer CellsThe WWOX tumor suppressor is essential for postnatal survival and normal bone metabolismWWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.Conditional Wwox deletion in mouse mammary gland by means of two Cre recombinase approaches.Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice.WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response.Common fragile site tumor suppressor genes and corresponding mouse models of cancer.miR-134 induces oncogenicity and metastasis in head and neck carcinoma through targeting WWOX gene.Epigenetic and genetic alterations affect the WWOX gene in head and neck squamous cell carcinoma.Systemic activation of K-ras rapidly induces gastric hyperplasia and metaplasia in miceStructural insights into the functional versatility of WW domain-containing oxidoreductase tumor suppressor.Allostery mediates ligand binding to WWOX tumor suppressor via a conformational switch.Biophysical basis of the binding of WWOX tumor suppressor to WBP1 and WBP2 adaptorsExposure to gastric juice may not cause adenocarcinogenesis of the esophagus.Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis.Molecular origin of the binding of WWOX tumor suppressor to ErbB4 receptor tyrosine kinase.Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype.WWOX gene and gene product: tumor suppression through specific protein interactions.WW domain-containing oxidoreductase's role in myriad cancers: clinical significance and future implications.The common fragile site FRA16D gene product WWOX: roles in tumor suppression and genomic stability.The tumor suppressor WW domain-containing oxidoreductase modulates cell metabolism.WWOX: a fragile tumor suppressor.WWOX, large common fragile site genes, and cancer.MicroRNA-153 promotes Wnt/β-catenin activation in hepatocellular carcinoma through suppression of WWOX.Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation.Tumor suppressor WWOX binds to ΔNp63α and sensitizes cancer cells to chemotherapyMapping of homozygous deletions in verified esophageal adenocarcinoma cell lines and xenografts.Fragile sites in cancer: more than meets the eye.Wwox inactivation enhances mammary tumorigenesis.Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells.WWOX modulates the ATR-mediated DNA damage checkpoint responseIdentification of a novel susceptibility locus at 16q23.1 associated with childhood acute lymphoblastic leukemia in Han Chinese.Tumor Suppressor WWOX inhibits osteosarcoma metastasis by modulating RUNX2 function.WWOX and p53 Dysregulation Synergize to Drive the Development of OsteosarcomaGenetic alterations of the WWOX gene in breast cancer.
P2860
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P2860
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
@en
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
@nl
type
label
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
@en
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
@nl
prefLabel
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
@en
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
@nl
P2093
P2860
P1433
P1476
Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo.
@en
P2093
Flavia Pichiorri
Haifa A Aqeilan
Louise Y Y Fong
Rami I Aqeilan
P2860
P304
P356
10.1158/0008-5472.CAN-07-1081
P407
P577
2007-06-01T00:00:00Z