Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors.
about
Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylationSoluble frizzled-related protein 1 is estrogen inducible in bone marrow stromal cells and suppresses the earliest events in lymphopoiesisWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentActivation of Wnt/β-catenin protein signaling induces mitochondria-mediated apoptosis in hematopoietic progenitor cellsSmall molecule p300/catenin antagonist enhances hematopoietic recovery after radiation.Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.Dysregulation of Frizzled 6 is a critical component of B-cell leukemogenesis in a mouse model of chronic lymphocytic leukemia.Wnt-related molecules and signaling pathway equilibrium in hematopoiesis.Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.Canonical Wnt signaling promotes early hematopoietic progenitor formation and erythroid specification during embryonic stem cell differentiationIdentification of Flt3⁺CD150⁻ myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential.T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling.The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells.Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development.MicroRNA-142-3p Negatively Regulates Canonical Wnt Signaling Pathway.Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivoThe canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis.Contrasting responses of lymphoid progenitors to canonical and noncanonical Wnt signals.Role of beta-catenin in B cell development and function.Canonical Wnt pathway signaling suppresses VCAM-1 expression by marrow stromal and hematopoietic cells.Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination.Role of Wnt canonical pathway in hematological malignancies.Multilayered specification of the T-cell lineage fate.Transcriptional drivers of the T-cell lineage program.Differential requirements for Wnt and Notch signaling in hematopoietic versus thymic niches.B-lineage transcription factors and cooperating gene lesions required for leukemia development.Wnt signaling in normal and malignant hematopoiesis.Targeting the canonical Wnt/β-catenin pathway in hematological malignancies.Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion.Interleukin-3-mediated regulation of β-catenin in myeloid transformation and acute myeloid leukemia.Inter-cellular adhesion disruption and the RAS/RAF and beta-catenin signalling in lung cancer progression.A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis.Transcription factor expression dynamics of early T-lymphocyte specification and commitment.Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance.Discrete roles of canonical and non-canonical Wnt signaling in hematopoiesis and lymphopoiesis.B-1 cells and B-1 cell precursors prompt different responses to Wnt signaling.
P2860
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P2860
Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Constitutively active beta-cat ...... phoid and myeloid progenitors.
@ast
Constitutively active beta-cat ...... phoid and myeloid progenitors.
@en
type
label
Constitutively active beta-cat ...... phoid and myeloid progenitors.
@ast
Constitutively active beta-cat ...... phoid and myeloid progenitors.
@en
prefLabel
Constitutively active beta-cat ...... phoid and myeloid progenitors.
@ast
Constitutively active beta-cat ...... phoid and myeloid progenitors.
@en
P2093
P2860
P1433
P1476
Constitutively active beta-cat ...... phoid and myeloid progenitors.
@en
P2093
Karla P Garrett
Paul W Kincade
Yoshihiro Baba
P2860
P304
P356
10.1016/J.IMMUNI.2005.10.009
P407
P577
2005-12-01T00:00:00Z