Characterization of functional domains within Smad4/DPC4 - Wikidata - wikimedia - TriplyDB

Characterization of functional domains within Smad4/DPC4

Characterization of functional domains within Smad4/DPC4

http://www.wikidata.org/entity/Q28238335

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The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads The transcriptional activity of CITED1 is regulated by phosphorylation in a cell cycle-dependent manner Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes RGC-32 mediates transforming growth factor-beta-induced epithelial-mesenchymal transition in human renal proximal tubular cells Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis Human Pancreatic Islets Express mRNA Species Encoding Two Distinct Catalytically Active Isoforms of Group VI Phospholipase A2 (iPLA2) [etc.]Transforming growth factor-beta regulates stearoyl coenzyme A desaturase expression through a Smad signaling pathway Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4 Crossing Smads TGF-beta: a mobile purveyor of immune privilege SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators The role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesis Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.Inhibiting scar formation in vitro and in vivo by adenovirus-mediated mutant Smad4: a preliminary report.Expression of functional Schistosoma mansoni Smad4: role in Erk-mediated transforming growth factor beta (TGF-beta) down-regulation.Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4.Sumoylation of Smad4, the common Smad mediator of transforming growth factor-beta family signaling.Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression.ΔNp73 enhances promoter activity of TGF-β induced genes.Smad proteins regulate transcriptional induction of the SM22alpha gene by TGF-beta.Smad3-mediated myocardin silencing: a novel mechanism governing the initiation of smooth muscle differentiation.G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation.Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases.Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis.Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells.Calcium-independent phospholipases A2 and their roles in biological processes and diseases.Loss of DPC4 expression and its correlation with clinicopathological parameters in pancreatic carcinoma.Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway.Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members.Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein.Protein kinase A modulates transforming growth factor-β signaling through a direct interaction with Smad4 protein SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.CREBZF, a novel Smad8-binding protein.Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus.Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4.Transforming growth factor-beta 1 regulation of collagenase-3 expression in osteoblastic cells by cross-talk between the Smad and MAPK signaling pathways and their components, Smad2 and Runx2.

P2860

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P2860

Characterization of functional domains within Smad4/DPC4

http://www.wikidata.org/entity/Q28238335

description

1997 nî lūn-bûn

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1997 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1997 թվականի մայիսին հրատարակված գիտական հոդված

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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name

Characterization of functional domains within Smad4/DPC4

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Characterization of functional domains within Smad4/DPC4

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Characterization of functional domains within Smad4/DPC4

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type

label

Characterization of functional domains within Smad4/DPC4

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Characterization of functional domains within Smad4/DPC4

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Characterization of functional domains within Smad4/DPC4

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Characterization of functional domains within Smad4/DPC4

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Characterization of functional domains within Smad4/DPC4

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Characterization of functional domains within Smad4/DPC4

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JBC.272.21.13690

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Journal of Biological Chemistry

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Characterization of functional domains within Smad4/DPC4

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P2093

A B Roberts

http://www.w3.org/2001/XMLSchema#string

M P de Caestecker

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P Hemmati

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R Ajmera

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R J Lechleider

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S Larisch-Bloch

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P2860

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

MADR1, a MAD-related protein that functions in BMP2 signaling pathways

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1

TGF beta signals through a heteromeric protein kinase receptor complex

Mechanism of activation of the TGF-beta receptor

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

A transcriptional partner for MAD proteins in TGF-beta signalling

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